PI51C_MOUSE   O70161


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UniProt:O70161

Recommended name:Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma

EC number:EC 2.7.1.68

Alternative names:(PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)

Cleaved into:

GeneID:18717

Gene names  (primary ):Pip5k1c

Gene names  (synonym ):Kiaa0589

Gene names  (ORF ):

Length:661

Mass:72408

Sequence:MELEVPDEAESAEAGAVTAEAAWSAESGAAAGMTQKKAGLAEAPLVTGQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNVLPRVVKMHLKFDLKGSTYKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQAEGAQSKADEKRPVAQKALYSTAMESIQGGAARGEAIETDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSSTVFRKSSSLKSSPSKKGRGALLAVKPLGPTAAFSASQIPSEREDVQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSPSDTSEQPRYRRRTQSSGQDGRPQEEPHAEDLQKITVQVEPVCGVGVVPKEEGAGVEVPPCGASAAASVEIDAASQASEPASQASDEEDAPSTDIYFPTDERSWVYSPLHYSARPASDGESDT

Tissue specificity:High expression in brain. Also detected in lung, thymus, heart, testicle, kidney and embryo. Highly expressed in forebrain, in particular in cerebellum, hippocampus and cerebral cortex. {ECO:0000269|PubMed:14741049, ECO:0000269|PubMed:20622009, ECO:0000269|PubMed:9535851}.

Induction:

Developmental stage:Expression increases during embryonic development and continued to steadily increase postnatally. {ECO:0000269|PubMed:20622009}.

Protein families:


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