A1AT6_MOUSE   Q9DCQ7


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UniProt:Q9DCQ7

Recommended name:Alpha-1-antitrypsin 1-6

EC number:

Alternative names:(Alpha-1 protease inhibitor 6) (Alpha-1-antiproteinase) (Serine protease inhibitor 1-6) (Serine protease inhibitor A1f) (Serpin A1f)

Cleaved into:

GeneID:68348

Gene names  (primary ):Serpina1f

Gene names  (synonym ):

Gene names  (ORF ):

Length:411

Mass:46337

Sequence:MTTPFSSHGLLLLVGLCCLLLITKTKHEKLYEDPSIDPFQCRKVALTICNVSITLFKKMAQLSGNGNILFSPIRVIAAISMLSLGSNGNLSKHILETLRFNKTGLPEAEIHKCFWYLLHSIHQTEETSSLQTGSSVFIHQDLTSVDKFVKGVKELYHSDMISINFTDSSQAKTQINNYVMEISQKAIVNIVKNLESDTFLAVVNYIIWNAKLDSNFGCRSVKVKDYHLGYGMTIKVPMIHNMAMHYLFRVGDLSSTVLMLTLLTGNFATYFIIPDPGKMQKVEQSLTYPHFRRMRRQLLTRLVDLEIPELSLSETHDLESMMSLLGITYVFNSGTNSSDMNDTLQKSFKVVSKAVLTIDEKGSKPSTNSCFKKLGSTDMGRMQLNRPFLIFIQDHTNDVPLFLGRVVNPQN

Tissue specificity:Expressed predominantly in epididymis where it is found in the epithelial cells of the caput, corpus and cauda epididymis. {ECO:0000269|PubMed:16707773}.

Induction:Expression decreases following castration. Administration of testosterone restores expression levels. {ECO:0000269|PubMed:16707773}.

Developmental stage:Expression increases gradually from post-natal day 1 to week 2, increases significantly from week 2 to week 4 and remains high thereafter. {ECO:0000269|PubMed:16707773}.

Protein families:Serpin family


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