A1AT6_MOUSE Q9DCQ7
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UniProt:Q9DCQ7
Recommended name:Alpha-1-antitrypsin 1-6
EC number:
Alternative names:(Alpha-1 protease inhibitor 6) (Alpha-1-antiproteinase) (Serine protease inhibitor 1-6) (Serine protease inhibitor A1f) (Serpin A1f)
Cleaved into:
GeneID:68348
Gene names (primary ):Serpina1f
Gene names (synonym ):
Gene names (ORF ):
Length:411
Mass:46337
Sequence:MTTPFSSHGLLLLVGLCCLLLITKTKHEKLYEDPSIDPFQCRKVALTICNVSITLFKKMAQLSGNGNILFSPIRVIAAISMLSLGSNGNLSKHILETLRFNKTGLPEAEIHKCFWYLLHSIHQTEETSSLQTGSSVFIHQDLTSVDKFVKGVKELYHSDMISINFTDSSQAKTQINNYVMEISQKAIVNIVKNLESDTFLAVVNYIIWNAKLDSNFGCRSVKVKDYHLGYGMTIKVPMIHNMAMHYLFRVGDLSSTVLMLTLLTGNFATYFIIPDPGKMQKVEQSLTYPHFRRMRRQLLTRLVDLEIPELSLSETHDLESMMSLLGITYVFNSGTNSSDMNDTLQKSFKVVSKAVLTIDEKGSKPSTNSCFKKLGSTDMGRMQLNRPFLIFIQDHTNDVPLFLGRVVNPQN
Tissue specificity:Expressed predominantly in epididymis where it is found in the epithelial cells of the caput, corpus and cauda epididymis. {ECO:0000269|PubMed:16707773}.
Induction:Expression decreases following castration. Administration of testosterone restores expression levels. {ECO:0000269|PubMed:16707773}.
Developmental stage:Expression increases gradually from post-natal day 1 to week 2, increases significantly from week 2 to week 4 and remains high thereafter. {ECO:0000269|PubMed:16707773}.
Protein families:Serpin family