BHE23_MOUSE Q8BGW3
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UniProt:Q8BGW3
Recommended name:Class E basic helix-loop-helix protein 23
EC number:
Alternative names:(bHLHe23) (Class B basic helix-loop-helix protein 4) (bHLHb4)
Cleaved into:
GeneID:140489
Gene names (primary ):Bhlhe23
Gene names (synonym ):Bhlhb4 H20
Gene names (ORF ):
Length:223
Mass:23701
Sequence:MAELKSLSGDSYLALSHSYTATGHAYAAARGPETTRGFGASGPGGDLPAAPASRVPAATVESSGEQSGDEDEAFERRRRRRGSGVAVDARRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQGLAAPVAAAPLTPFGQAAIYPFSAGTALGPCPDKCATFSGSPSALCKHCGEKP
Tissue specificity:Expressed in brain and retina.
Induction:
Developmental stage:Expression is confined to regions of the developing nervous system and pancreas. At 13 dpc expressed at lower levels in the trigeminal ganglion, the ganglionic eminence, the ventral neural tube, and dorsal root ganglia. Expressed at moderate levels in the tectum of the embryonic midbrain. Most prominent expression is in the diencephalon, where it flanks either side of the roof of the third ventricle, dorsal/caudal to the dorsal thalamus. Detected in the pancreas during the time when most of the pancreatic endocrine cell types are beginning to differentiate and endocrine precursor cells remain loosely associated with the duct epithelium until they begin to form aggregates late in development. {ECO:0000269|PubMed:11863370}.
Protein families: