MCH_MOUSE P56942
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UniProt:P56942
Recommended name:Pro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid
EC number:
Alternative names:(NGE) (Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine (NEI) (Neuropeptide E-I); Melanin-concentrating hormone (MCH)]
Cleaved into:
GeneID:110312
Gene names (primary ):Pmch
Gene names (synonym ):Mch
Gene names (ORF ):
Length:165
Mass:18516
Sequence:MAKMTLSSYMLMLAFSLFSQGILLSASKSIRNLEDDIVFNTFRMGKAFQKEDTAERSVVAPSLEQYKNDESGFMNDDDNKNSKNTGSKQNLVTHGLPLSLAVKPYLALKGSVAFPAENGVQNAESTQEKREIGDEENSAKFPIGRRDFDMLRCMLGRVYRPCWQV
Tissue specificity:Predominantly expressed in hypothalamus. Also found in heart, intestine, spleen and testis (spermatogonia, early spermatocytes and Sertoli cells). In brain only mature MCH and NEI peptides are present. In peripheral tissues a large product, encompassing the NEI and MCH domains of the precursor, is found predominantly. {ECO:0000269|PubMed:8724342}.
Induction:
Developmental stage:Expression is enhanced between postnatal days 10 and 15.
Protein families:MCH family