MCH_MOUSE   P56942


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UniProt:P56942

Recommended name:Pro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid

EC number:

Alternative names:(NGE) (Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine (NEI) (Neuropeptide E-I); Melanin-concentrating hormone (MCH)]

Cleaved into:

GeneID:110312

Gene names  (primary ):Pmch

Gene names  (synonym ):Mch

Gene names  (ORF ):

Length:165

Mass:18516

Sequence:MAKMTLSSYMLMLAFSLFSQGILLSASKSIRNLEDDIVFNTFRMGKAFQKEDTAERSVVAPSLEQYKNDESGFMNDDDNKNSKNTGSKQNLVTHGLPLSLAVKPYLALKGSVAFPAENGVQNAESTQEKREIGDEENSAKFPIGRRDFDMLRCMLGRVYRPCWQV

Tissue specificity:Predominantly expressed in hypothalamus. Also found in heart, intestine, spleen and testis (spermatogonia, early spermatocytes and Sertoli cells). In brain only mature MCH and NEI peptides are present. In peripheral tissues a large product, encompassing the NEI and MCH domains of the precursor, is found predominantly. {ECO:0000269|PubMed:8724342}.

Induction:

Developmental stage:Expression is enhanced between postnatal days 10 and 15.

Protein families:MCH family


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