ABC8A_MOUSE Q8K442
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UniProt:Q8K442
Recommended name：ATP-binding cassette sub-family A member 8-A
EC number：
Alternative names：
Cleaved into：
GeneID：217258
Gene names (primary )：Abca8a
Gene names (synonym )：
Gene names (ORF )：
Length：1620
Mass：184180
Sequence：MVKREINVCQQTWALLCKNLLRKKRLKRDTFLEFLYTALILLSLILFLQLHEVYDFSSLPDVDLGRIDSFNDSTFMIVYTPITPTTQRIMDRVSLVSYMTGRKILASPNEENMTELISMRFSDVVGVIFTNAYSYNLKFIKGARIPTIKEHQDHTAHCHSYGEIIYCGLSEFWRDGFVALQAAINAAIIEVTTNHSVMEEMMSLTGKYIKIDSFVGQEGTTTDCFLFFCIIRFSPLTYYISAGVTRERKKMKGLMAVMGLRDSAFWLSWGLLYGVIVFVVTLLSTTIVKLVQFVFLTGFMVIFSLFFFYGLSLISLSFLMSVLLKKSFLTDLVVFLLTVSCGSLGFTALYRYLPVSLEWLLSLLSPFAFMLGMVQLLRLDYDVNSNADPMGNPNEVIGTIFMLFFDGVFYLLLTFYFEKVLPSKSFHDKTYWHACKSHFFLIDYSFYIRTALDNETDYEFSDDSFEPVSMEFHGKEAIRIRNLTKDYIQKSKRTEALKDLTLDVYKGQITAILGHSGAGKSTLLNVLSGLCVPTKGWVTIHNNKLSEMTDLENISKLTGVCPQCNVQFDFLTVRENLRLFAKIKGIQAHEVDNEVQRVLLELDMKNTQNILVQNLSGGQKRKLTFGIAILGDPQIFLLDEPTAGLDPFSRHRVWNFLKERRADRVVLFSTQFMDEADILADRKVFISKGKLKCAGSSLFLKKKWGIGYHLSLQLSETCVHERITSLVKQHIPDSKLSAESEGKLSYILPLERTNKFPDLYRDLERSPDLGIENYGVSITTLTEVFLKLEGKSSIDQSDIGMTEDVQAGGARSPERFAEVEQLVSLLNGRCKMKGGMALWWQQLCAVTRLRFLKLKHERKSIVILILVLGIGLLHILSANIYRMVRQSDYCWELAPHMYFLTPGQQPQPPLTNLLIVNKTGAKIDDFIHSLEQQNIALEVDAFGTRNGTEDSQYNGAIILSGDEKNYNFTLACNTKRLNCFPVLVDIVSNGLLGLFAPSAHIQTDRSTFPEENDHRKFDYLAYFFLWVLLMACVPPYISMTSIDDYKNRAQFQLWISGLSPSAYWFGQALFEVPVYCALILSIFIAFYASAPPESKFTVGDLFIQILYVGGYAMSVIFMTYVISFIYRKGRKNSGLWSLCFYIVSFFSMCFMLIDYFRDISLFVLIALVPPATLGGCTLLHFENREFSEIIFEPEREYSYLFFLAPLLHFAIFVVILRCMERKFGMKTMRTDPVFRISPRSDRVFNNPEDPDGEDEDVSQERVWTANALTSADFQEKPAIIASCLRKEYKGKKKCFVLKSKKKIATRNISFCVRKGEVVGLLGHNGAGKSTSIKMITGETKPSAGQVLLKGSSTGDTPGFLGYCPQENALWLNLTVREHLEIFAAIKGMRKSDANVAIERLADALKLQDQLKSPVKTLSEGVKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIQATFSNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKEYLLEMKVKTPSQVEPLNTEIMRLFPQAARQERYSSLMVYKLPREDVQPLSQAFFKLETVKQSFDLEEYSLSQSTLEQVFLELSKEQELDGFEEELDPSVKWKLLPQEEA
Tissue specificity：Expressed in lung, heart, liver, skeletal muscle and testis. {ECO:0000269|PubMed:12532264, ECO:0000269|PubMed:16445568}.
Induction：Down-regulated by digoxin. {ECO:0000269|PubMed:16445568}.
Developmental stage：Expression is first detected at 17 dpc. {ECO:0000269|PubMed:12532264}.
Protein families：ABC transporter superfamily, ABCA family