AP2D_MOUSE Q91ZK0
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UniProt:Q91ZK0
Recommended name:Transcription factor AP-2-delta
EC number:
Alternative names:(AP2-delta) (Activating enhancer-binding protein 2-delta)
Cleaved into:
GeneID:226896
Gene names (primary ):Tfap2d
Gene names (synonym ):Tcfap2d
Gene names (ORF ):
Length:452
Mass:49548
Sequence:MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGIVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHANSEKAPLRKASEAAVKEGKTEKTD
Tissue specificity:Expressed in both embryonic and newborn brain. {ECO:0000269|PubMed:11522791}.
Induction:
Developmental stage:Expression is first detected at 9.5 dpc in the central nervous system and the developing heart. The signal detected in heart persists through to 10.5 dpc. Diffusely expressed in developing brain at 10.5 dpc to 11.5 dpc, but by 13.5 dpc expression is mostly confined to the midbrain and forebrain. Also expressed in the spinal cord at 10.5 dpc, and in retinal epithelium from 13.5 dpc to 16.5 dpc. No signals detected in tissues such as the neural crest, facial mesenchyme, and limbs where other Tfap2 genes are expressed. {ECO:0000269|PubMed:12711551}.
Protein families:AP-2 family