TWF2_MOUSE Q9Z0P5
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UniProt:Q9Z0P5
Recommended name:Twinfilin-2
EC number:
Alternative names:(A6-related protein) (mA6RP) (Twinfilin-1-like protein)
Cleaved into:
GeneID:23999
Gene names (primary ):Twf2
Gene names (synonym ):Ptk9l
Gene names (ORF ):
Length:349
Mass:39471
Sequence:MAHQTGIHATEELKEFFAKARAGSIRLIKVIIEDEQLVLGASQEPVGRWDQDYDRAVLPLLDAQEPCYLLFRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDELFGTVKDDLSLAGYQKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLKQKTVNYIQLKLDLERETIELVHTEPTNVAQLPSRIPRDAARYHFFLYKHTHEGDALESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFQLEIAKKIEIGDGAELTAEFLYDEVHPKQHAFKQAFAKPKGPGGKRGHKRLIRGPGENGEDS
Tissue specificity:Isoform 1 is ubiquitously expressed (at protein level). Isoform 2 expression is restricted to heart and skeletal muscle where it is the predominant form. {ECO:0000269|PubMed:10406962, ECO:0000269|PubMed:18837697}.
Induction:
Developmental stage:Expression was relatively weak during all of the embryonic stages. At 14.5 dpc, a slight increase in the expression could be observed in heart, CNS, and PNS. At 18.5 dpc, it is strongly expressed in the inner ear, hair cells and in the head muscles. No expression is detected in the nasal epithelium or in the skin keratinocytes. {ECO:0000269|PubMed:12807912}.
Protein families:Actin-binding proteins ADF family, Twinfilin subfamily