TWF1_MOUSE Q91YR1
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UniProt:Q91YR1
Recommended name：Twinfilin-1
EC number：
Alternative names：(Protein A6)
Cleaved into：
GeneID：19230
Gene names (primary )：Twf1
Gene names (synonym )：Ptk9
Gene names (ORF )：
Length：350
Mass：40079
Sequence：MSHQTGIQASEDVKEIFARARNGKYRLLKISIENEQLVVGSCSPPSDSWEQDYDSFVLPLLEDKQPCYVLFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDEVFGTVKEDVSLHGYKKYLLSQSSPAPLTAAEEELRQIKINEVQTDVSVDTKHQTLQGVAFPISRDAFQALEKLSKKQLNYVQLEIDIKNETIILANTENTELRDLPKRIPKDSARYHFFLYKHSHEGDYLESVVFIYSMPGYTCSIRERMLYSSCKSPLLEIVERQLQMDVIRKIEIDNGDELTADFLYDEVHPKQHAHKQSFAKPKGPAGKRGIRRLIRGPAEAEATTD
Tissue specificity：Widely expressed with highest levels in brain, liver and kidney. Also expressed in heart, lung and testis. Not detected in spleen or skeletal muscle. {ECO:0000269|PubMed:10669753, ECO:0000269|PubMed:12807912, ECO:0000269|PubMed:9249064}.
Induction：
Developmental stage：Expression was widespread throughout the embryonic stages analyzed; 10.5 dpc, 12.5 dpc, 14.5 dpc and 18.5 dpc. At 14.5 dpc, strongest expression was observed in the developing central and peripheral nervous system (CNS and PNS, respectively) and in the olfactory sensory epithelium. In the CNS, the proliferating neuronal precursors in the ventricular zone expressed it more than the postmitotic neurons. At 18.5 dpc, highest expression levels were detected in the mechanosensory hair cells of the inner ear and in the differentiated keratinocytes of the skin. {ECO:0000269|PubMed:12807912}.
Protein families：Actin-binding proteins ADF family, Twinfilin subfamily