NPAS2_MOUSE   P97460


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UniProt:P97460

Recommended name:Neuronal PAS domain-containing protein 2

EC number:

Alternative names:(Neuronal PAS2)

Cleaved into:

GeneID:18143

Gene names  (primary ):Npas2

Gene names  (synonym ):

Gene names  (ORF ):

Length:816

Mass:90916

Sequence:MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFVIVVTTDGSIIYVSDSITPLLGHLPADVMDQNLLNFLPEQEHSEVYKILSSHMLVTDSPSPEFLKSDNDLEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCHVPLGKDVCFIATVRLATPQFLKEMCVADEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYNYYHIDDLELLARCHQHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVERRQELALEDPPTEAMHPSAVKEKDSSLEPPQPFNALDMGASGLPSSPSPSASSRSSHKSSHTAMSEPTSTPTKLMAENSTTALPRPATLPQELPVQGLSQAATMPTALHSSASCDLTKQLLLQSLPQTGLQSPPAPVTQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELHKIQEQLCLVQDSNVQMFLQQPAVSLSFSSTQRPAAQQQLQQRPAAPSQPQLVVNTPLQGQITSTQVTNQHLLRESNVISAQGPKPMRSSQLLPASGRSLSSLPSQFSSTASVLPPGLSLTTIAPTPQDDSQCQPSPDFGHDRQLRLLLSQPIQPMMPGSCDARQPSEVSRTGRQVKYAQSQVMFPSPDSHPTNSSASTPVLLMGQAVLHPSFPASRPSPLQPAQAQQQPPPYLQAPTSLHSEQPDSLLLSTFSQQPGTLGYAATQSTPPQPPRPSRRVSRLSES

Tissue specificity:Expressed in the retinal ganglion cells (at protein level). Expressed in the hypothalamic suprachiasmatic nuclei (SCN) of the brain. Also found in spinal cord, and to a lesser extent in colon, small intestine and uterus. Exhibits a diurnal variation in its expression in the brain (PubMed:29163035). {ECO:0000269|PubMed:17417633, ECO:0000269|PubMed:24048828, ECO:0000269|PubMed:29163035, ECO:0000269|PubMed:9012850}.

Induction:Expression in the retinal ganglion cells and heart oscillates in a circadian manner. {ECO:0000269|PubMed:14645221, ECO:0000269|PubMed:24048828}.

Developmental stage:First detected 3 days after birth. {ECO:0000269|PubMed:9012850}.

Protein families:


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