NPAS2_MOUSE P97460
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UniProt:P97460
Recommended name:Neuronal PAS domain-containing protein 2
EC number:
Alternative names:(Neuronal PAS2)
Cleaved into:
GeneID:18143
Gene names (primary ):Npas2
Gene names (synonym ):
Gene names (ORF ):
Length:816
Mass:90916
Sequence:MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFVIVVTTDGSIIYVSDSITPLLGHLPADVMDQNLLNFLPEQEHSEVYKILSSHMLVTDSPSPEFLKSDNDLEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCHVPLGKDVCFIATVRLATPQFLKEMCVADEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYNYYHIDDLELLARCHQHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVERRQELALEDPPTEAMHPSAVKEKDSSLEPPQPFNALDMGASGLPSSPSPSASSRSSHKSSHTAMSEPTSTPTKLMAENSTTALPRPATLPQELPVQGLSQAATMPTALHSSASCDLTKQLLLQSLPQTGLQSPPAPVTQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELHKIQEQLCLVQDSNVQMFLQQPAVSLSFSSTQRPAAQQQLQQRPAAPSQPQLVVNTPLQGQITSTQVTNQHLLRESNVISAQGPKPMRSSQLLPASGRSLSSLPSQFSSTASVLPPGLSLTTIAPTPQDDSQCQPSPDFGHDRQLRLLLSQPIQPMMPGSCDARQPSEVSRTGRQVKYAQSQVMFPSPDSHPTNSSASTPVLLMGQAVLHPSFPASRPSPLQPAQAQQQPPPYLQAPTSLHSEQPDSLLLSTFSQQPGTLGYAATQSTPPQPPRPSRRVSRLSES
Tissue specificity:Expressed in the retinal ganglion cells (at protein level). Expressed in the hypothalamic suprachiasmatic nuclei (SCN) of the brain. Also found in spinal cord, and to a lesser extent in colon, small intestine and uterus. Exhibits a diurnal variation in its expression in the brain (PubMed:29163035). {ECO:0000269|PubMed:17417633, ECO:0000269|PubMed:24048828, ECO:0000269|PubMed:29163035, ECO:0000269|PubMed:9012850}.
Induction:Expression in the retinal ganglion cells and heart oscillates in a circadian manner. {ECO:0000269|PubMed:14645221, ECO:0000269|PubMed:24048828}.
Developmental stage:First detected 3 days after birth. {ECO:0000269|PubMed:9012850}.
Protein families: