TBR1_MOUSE Q64336
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UniProt:Q64336
Recommended name:T-box brain protein 1
EC number:
Alternative names:(T-brain-1) (TBR-1) (TES-56)
Cleaved into:
GeneID:21375
Gene names (primary ):Tbr1
Gene names (synonym ):
Gene names (ORF ):
Length:681
Mass:73940
Sequence:MQLEHCLSPSIMLSKKFLNVSSSYPHSGGSELVLHDHPIISTTDNLERSSPLKKITRGMTNQSDTDNFPDSKDSPGDVQRSKLSPVLDGVSELRHSFDGSAADRYLLSQSSQPQSAATAPSAMFPYPSQHGPAHPAFSIGSPSRYMAHHPVITNGAYNSLLSNSSPQGYPTAGYPYPQQYGHSYQGAPFYQFSSTQPGLVPGKAQVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHWRFQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQMVVLQSLHKYQPRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDTIYTGCDMDRLTPSPNDSPRSQIVPGARYAMAGSFLQDQFVSNYAKARFHPGAGAGPGPGTDRSVPHTNGLLSPQQAEDPGAPSPQRWFVTPANNRLDFAASAYDTATDFAGNAATLLSYAAAGVKALPLQAAGCTGRPLGYYADPSGWGARSPPQYCGAKSGSVLPCWPNSAAAAARMAGANPYLGEEAEGLAAERSPLAPAAEDAKPKDLSDSSWIETPSSIKSIDSSDSGIYEQAKRRRISPADTPVSESSSPLKSEVLAQRDCEKNCAKDIGGYYGFYSHS
Tissue specificity:Expressed in the developing and adult cortex (PubMed:11239428). Expressed in the olfactory bulbs (PubMed:9883721). {ECO:0000269|PubMed:11239428, ECO:0000269|PubMed:9883721}.
Induction:
Developmental stage:First detected around day 10 of embryonic development in the preplate, at day 12.5, in the cortical plate and intermediate zone, and from day 16.5 to 18.5, in a rostro-caudal gradient in the subplate. In the thalamus, expression is first observed at postnatal stage, P7, and weak expression continues in later postnatal and adult stages.
Protein families: