LBX2_MOUSE Q9WUN8
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UniProt:Q9WUN8
Recommended name:Transcription factor LBX2
EC number:
Alternative names:(Ladybird homeobox 2) (Ladybird homeobox protein homolog 2)
Cleaved into:
GeneID:16815
Gene names (primary ):Lbx2
Gene names (synonym ):Lbx2h
Gene names (ORF ):
Length:195
Mass:20917
Sequence:MNSVHQRRTPFSIADILGPSMVPEAPSAPQLPEAGPDPASPLCALEELASKTFLGHSPRATPQPSEGRAAPEAPPGPGAGVRRRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLAARLGLANAQVVTWFQNRRAKLKRDVEEMRADVASLCGLSPGVLCYPALPDSTSSPDPGPSGPDSEPNLSDEEIQVDD
Tissue specificity:Expressed in the developing urogenital system, eye and brain. {ECO:0000269|PubMed:10473138}.
Induction:By PAX3 which regulates its expression. {ECO:0000269|PubMed:17492753}.
Developmental stage:First detected at 10.5 dpc in the gonadal component of the urogenital ridge. Expression dramatically increases by 11.5 dpc in the urogenital ridges and in the cranial surface ectoderm. At this time, it is also expressed in the trigeminal ganglion and nodose ganglion. At later stages, it is expressed in the brain and organs derived from the urogenital ridge, including the gonadal tubercle, kidneys, and adrenal glands. From 14.5 dpc to birth, expression is evident in the developing retinal neuroepithelium and the vibrissa. {ECO:0000269|PubMed:10473138, ECO:0000269|PubMed:11386758}.
Protein families: