CGL_MOUSE Q8VCN5
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UniProt:Q8VCN5
Recommended name:Cystathionine gamma-lyase
EC number:EC 4.4.1.1
Alternative names:(Cysteine-protein sulfhydrase) (Gamma-cystathionase)
Cleaved into:
GeneID:107869
Gene names (primary ):Cth
Gene names (synonym ):
Gene names (ORF ):
Length:398
Mass:43567
Sequence:MQKDASLSGFLPSFQHFATQAIHVGQEPEQWNSRAVVLPISLATTFKQDFPGQSSGFEYSRSGNPTRNCLEKAVAALDGAKHSLAFASGLAATITITHLLKAGDEIICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIGACAQIVHKRGDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNSRLRFLQNSLGAVPSPFDCYLCCRGLKTLQVRMEKHFKNGMAVARFLETNPRVEKVVYPGLPSHPQHELAKRQCSGCPGMVSFYIKGALQHAKAFLKNLKLFTLAESLGGYESLAELPAIMTHASVPEKDRATLGINDTLIRLSVGLEDEQDLLEDLDRALKAAHP
Tissue specificity:Detected in liver and kidney, and at lower levels in small intestine (at protein level). Highly expressed in liver and kidney. detected at lower levels in stomach, small intestine and adipose tissue. {ECO:0000269|PubMed:15038791}.
Induction:
Developmental stage:First detected at low levels in embryonic liver after 12.5 days of embryonic development. Highly expressed in liver and kidney after 18.5 days of embryonic development. Expressed at high levels in liver and kidney after birth and in adults.
Protein families:Trans-sulfuration enzymes family