PRG4_MOUSE Q9JM99
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UniProt:Q9JM99
Recommended name：Proteoglycan 4
EC number：
Alternative names：(Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan)
Cleaved into：Proteoglycan 4 C-terminal part
GeneID：96875
Gene names (primary )：Prg4
Gene names (synonym )：Msf Szp
Gene names (ORF )：
Length：1054
Mass：115996
Sequence：MGWKILPVCLSLLLPVVLIQQVSSQDLSSCAGRCGEGYSRDATCNCDYNCQHYMECCPDFKRVCSPELSCKGRCFESFARGRECDCDSQCKQYGKCCADYDSFCEEVHNSTSPSSKTAPTPAGASDTIKSTTKRSPKSPTTRTIKVVESEELTEEHSDSENQESSSSSSSSSSTIRKIKSSKNSANRELQKNPNVKDNKKNTPKKKPNPEPPAVDEAGSGLDNGEFKLTPPPPDPPTTPHSKVATSPKTTAAKPVTPKPSLAPNSETSKEASLASNKETTVETKETTATNKQSSASKKKTTSVKETRSAEKTSDKDVEPTSTTPKNSAPTTTKKPVTTTKESKFLPLPQEPEPTTAKEPPPTTKKPEPTTRKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPPPTTKKPEPTTPKEPGPTTPKEPEPTTTKEPEPTTTKEPESTTRKEPEPTTPKEPEPTTPKEPEPTTLKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKKPEPTTPKEPVPTTPKEPEPTTPKEPEPTTPKEPEPTTRKEPEPTTPKEPEPTTPKEPEPTTPKKPEPTTTSPKTTTLKATTLAPKVTAPAEEIQNKPEETTPASEDSDDSKTTLKPQKPTKAPKPTKKPTKAPKKPTSTKKPKTPKTRKPKTTPSPLKTTSATPELNTTPLEVMLPTTTIPKQTPNPETAEVNPDHEDADGGEGEKPLIPGPPVLFPTAIPGTDLLAGRLNQGININPMLSDETNLCNGKPVDGLTTLRNGTLVAFRGHYFWMLNPFRPPSPPRRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDVVDPGYPKQIVKGFGGLTGKIVAALSIAKYKDRPESVYFFKRGGNIQQYTYKQEPMKKCTGRRPAINYSVYGEAAQVRRRRFERAVGPFQTHTFRIHYSVPMRVSYQDKGFLHNEVKVSTMWRGFPNVVTSAITLPNIRKPDGYDYYAFSKDQYYNIDVPTRTARAITTRSGQTLSKIWYNCP
Tissue specificity：Highly expressed in cartilage, bone and liver and weakly expressed in heart, brain and muscle. Expressed in the surface chondrocytes and in synovial intimal cells. Isoform B is expressed in bone, small intestine, muscle, testis, heart, liver and lung. Isoform C and isoform D are widely expressed. {ECO:0000269|PubMed:11124536, ECO:0000269|PubMed:15719068}.
Induction：
Developmental stage：First detected at the forming joint surface from 15.5 dpc, after cavitation has begun. At later stages of morphogenesis, strong expression is observed in cartilage surface cells (superficial zone chondocytes) and in the newly forming synovium. {ECO:0000269|PubMed:15719068}.
Protein families：