IKZF1_MOUSE Q03267
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UniProt:Q03267
Recommended name：DNA-binding protein Ikaros
EC number：
Alternative names：(Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Cleaved into：
GeneID：
Gene names (primary )：Ikzf1
Gene names (synonym )：Ikaros Lyf1 Zfpn1a1 Znfn1a1
Gene names (ORF )：
Length：517
Mass：57336
Sequence：MDVDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSDRGMGSNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIVCIGPNVLMVHKRSHTERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGVCPVIKEETNHNEMAEDLCKIGAERSLVLDRLASNVAKRKSSMPQKFLGDKCLSDMPYDSANYEKEDMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPSDGPPRSNHSAQDAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHINPHARNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLS
Tissue specificity：Strongly expressed in T-cells and their progenitors,in B-cells, and in all early embryonic retinal progenitor cells (RPCs). Isoforms V and VI are the predominant isoforms in lymphocytes. {ECO:0000269|PubMed:1439790, ECO:0000269|PubMed:18940586, ECO:0000269|PubMed:7935426}.
Induction：
Developmental stage：First detected in fetal liver and embryonic thymus. {ECO:0000269|PubMed:1439790}.
Protein families：Ikaros C2H2-type zinc-finger protein family