BFSP1_MOUSE A2AMT1
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UniProt:A2AMT1
Recommended name：Filensin
EC number：
Alternative names：(Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 95) (CP95)
Cleaved into：Filensin C-terminal fragment; Filensin N-terminal fragment
GeneID：12075
Gene names (primary )：Bfsp1
Gene names (synonym )：
Gene names (ORF )：
Length：669
Mass：73669
Sequence：MYRRSYVFQARQERYERAQPAGPAAQPGGTAPGLAALQALGERVAVQVQRARALQQRHAGLRRQLDAFQRLGEQPGPEDALARHVEANLQRARDLTAEHARLERQEAEAQRALDEFRSKYENECECQLVLKEMLERLNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQVSLVTGMRESGLLMQEKLFTEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDEELQLYNEQIENLRKEIEEAERSLERSSYDCRQLAVAQQTLRNELDRYHRIIEIEGSRLSSVFIETPISLITPSHGAPLSLGSSVKDLARAVQDITAAKPRQKALPKSLPKRKEIIAQDKVEETLEDAPLKPPQEPKALQVERKAEGGSQPGAGGGHGVSPTQEGGPEDVPDGGQISKAFGKLCKVVKERVSGHKEPEPEPPTDLFTKGRHVLVTGESSFVDPEFYSSSIPARGGVVISIEEDSMHHDGHVEPSPGQPMPPVENGQGVPQGREGDHSNHQQGTDKNGLRAKEPKDLEEKDDDGKKEAEGSRRPCPVIIPGPDEPSTSHSQTSGSNQGGPVGPASKSSSLLAKGPSKALSIKKVEVVESIEKISTESIQTYEETSVIVETLIGKSKGNKKLGEKSLPDTRA
Tissue specificity：Detected in eye lens fiber cells (at protein level) (PubMed:14985306, PubMed:19029034, PubMed:21745462). Expressed in retinal lens epithelial cells (at protein level) (PubMed:27559293). {ECO:0000269|PubMed:14985306, ECO:0000269|PubMed:19029034, ECO:0000269|PubMed:21745462, ECO:0000269|PubMed:27559293}.
Induction：
Developmental stage：First expressed in retinal lens fiber cells during elongation and differentiation, becoming localized to the cytoplasm as fiber cells mature and the beaded filament network forms at 3 weeks of age. {ECO:0000269|PubMed:19029034}.
Protein families：Intermediate filament family