NUAK2_MOUSE Q8BZN4
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UniProt:Q8BZN4
Recommended name:NUAK family SNF1-like kinase 2
EC number:EC 2.7.11.1
Alternative names:(Omphalocele kinase 2)
Cleaved into:
GeneID:74137
Gene names (primary ):Nuak2
Gene names (synonym ):Omphk2
Gene names (ORF ):
Length:639
Mass:70675
Sequence:MESVALLQRPSQAPSASALASESARPLADGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWVNWGYTTGVGEQEALREGGHPSGDFGRASMADWLRRSSRPLLENGAKVCSFFKQHVPGGGSTVPGLERQHSLKKSRKENDMAQNLQGDPAEDTSSRPGKSSLKLPKGILKKKSSTSSGEVQEDPQELRPVPDTPGQPVPAVSLLPRKGILKKSRQRESGYYSSPEPSESGELLDASDVFVSGDPVEQKSPQASGLLLHRKGILKLNGKFSRTALEGTTPSTFGSLDQLASSHPAARPSRPSGAVSEDSILSSESFDQLDLPERLPETPLRGCVSVDNLRGLEQPPSEGLKRWWQESLGDSCFSLTDCQEVTAAYRQALGICSKLS
Tissue specificity:
Induction:
Developmental stage:First expressed in the anterior neuroectoderm at 7.5 dpc. At 8.5 dpc, the expression is present in future forebrain and midbrain regions. At 9.5 dpc, the expression is intense in the forebrain and midbrain with a sharp caudal boundary at the isthmic region; a low level of the expression is found throughout the neuroectoderm. Not expressed in the ventral body wall. {ECO:0000269|PubMed:16715502}.
Protein families:Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily