VWC2L_MOUSE   Q505H4


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UniProt:Q505H4

Recommended name:von Willebrand factor C domain-containing protein 2-like

EC number:

Alternative names:(Brorin-like)

Cleaved into:

GeneID:320460

Gene names  (primary ):Vwc2l

Gene names  (synonym ):

Gene names  (ORF ):

Length:222

Mass:24528

Sequence:MALHIHEACILLLVIPGLVTSAAISHEDYPADEGDQASSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPIYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDDCNICHCHNGDWWKPAQCSKRECQGKQTV

Tissue specificity:Predominantly expressed in the brain (at protein level). Also detected in bones, including femur and calvaria, heart, lung and kidney. Isoform 5 is predominant in lung and heart, compared to isoforms 1 and 3. Isoform 4 is expressed in femur and calvaria at higher levels than isoforms 1 and 5. Isoforms 1 and 4 are expressed at higher levels than isoform 5 in kidney and brain. {ECO:0000269|PubMed:19852960, ECO:0000269|PubMed:22209847, ECO:0000269|PubMed:22632720}.

Induction:

Developmental stage:From 12.5 dpc to 18.5 dpc, expressed in the developing neural tissues, including several discrete regions in the forebrain, midbrain and hindbrain, as well as in the spinal cord. May be up-regulated in the course of preosteblast differentiation and matrix mineralization. {ECO:0000269|PubMed:19852960, ECO:0000269|PubMed:22209847}.

Protein families:


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