WTIP_MOUSE Q7TQJ8
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UniProt:Q7TQJ8
Recommended name：Wilms tumor protein 1-interacting protein
EC number：
Alternative names：(WT1-interacting protein)
Cleaved into：
GeneID：101543
Gene names (primary )：Wtip
Gene names (synonym )：
Gene names (ORF )：
Length：398
Mass：42254
Sequence：MQRSRTAADDAALLLAGLGLRESEPTAGSPGRVRRGPRAVDEAAPASGRRGKGGCGGPEAAPDVPSRPERGPRASLAGSDGGSARSSGISLGYDQRHGPGPGPPSGGSARSSVSSLGSRGSAGACADLLPPGVGPAPARSPEPAQFPFPLPSLPLPPGREGGPSAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGARQACQAMGSLYHTDCFICDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVDNNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVECYHCEDCGLQLSGEEGRRCYPLEGHLLCRRCHLRRLGQGPLPSPAVHVTEL
Tissue specificity：Expressed in kidney, lung, eye and ovary. In kidney, restricted to podocytes. {ECO:0000269|PubMed:14736876, ECO:0000269|PubMed:20086015}.
Induction：
Developmental stage：From 9.5 to 11.5 dpc, expressed in the branchial arches, otic vesicle, limb buds, somites, craniofacial mesenchyme and tail buds. At 14.5 dpc, expressed in the developing tongue, nasal cavity, palate, adrenal gland, in the forebrain, dorsal root ganglia and in the somites. At 14.5 dpc, also detected in lung, rib cartilage, kidney and intestine (at protein level). In the kidney, expression peaks at 15 to 16 dpc and decreases thereafter, but persists in adulthood. {ECO:0000269|PubMed:14736876, ECO:0000269|PubMed:19785987}.
Protein families：Zyxin/ajuba family