ARFG2_MOUSE Q99K28
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UniProt:Q99K28
Recommended name：ADP-ribosylation factor GTPase-activating protein 2
EC number：
Alternative names：(ARF GAP 2) (GTPase-activating protein ZNF289) (Zinc finger protein 289)
Cleaved into：
GeneID：77038
Gene names (primary )：Arfgap2
Gene names (synonym )：Zfp289 Znf289
Gene names (ORF )：
Length：520
Mass：56598
Sequence：MAASPSKTEIQTIFKRLRAIPTNKACFDCGAKSPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWSWLQLRCMQVGGNANATAFFRQHGCMANDANTKYTSRAAQMYREKIRQLGSAALTRHGTDLWIDSMNSAPSHSPEKKDSDFFTEHTQAPAWDTAATDPSGTQQPALPSESSSLAQPEQGPNTDLLGTSPQASLELKSSIIGKKKPAAAKKGLGAKKGLGAQKVSNQSFTEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLVSRSSISHSVLSEMQMIEQETPLSAKSSRSQLDLFDDVGTFASGPPKYKDNPFSLGETFGSRWDSDAAWGMDRVEEKEPEVTISSIRPISERTASRREVETRSSGLESSEARQKFAGAKAISSDMFFGREVDSEYEARSRLQQLSGSSAISSSDLFGNMDGAHGGGTVSLGNVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY
Tissue specificity：Highly expressed in liver, heart and kidney. Low expression in skeletal muscle and spleen. {ECO:0000269|PubMed:11278321}.
Induction：
Developmental stage：High levels in mammary glands of virgin mice and in mammary glands of pregnant mice associated with extensive proliferation of ductal cells and lobulo-alveolar development. Expression declines at the beginning of lactation when the glands fully differentiate. No expression after day 2 of lactation until day 21. Expression may be controlled by ID1. {ECO:0000269|PubMed:11278321}.
Protein families：