SCD2_MOUSE P13011
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UniProt:P13011
Recommended name：Stearoyl-CoA desaturase 2
EC number：EC 1.14.19.1
Alternative names：(Acyl-CoA desaturase 2) (Delta(9)-desaturase 2) (Delta-9 desaturase 2) (Fatty acid desaturase 2)
Cleaved into：
GeneID：20250
Gene names (primary )：Scd2
Gene names (synonym )：
Gene names (ORF )：
Length：358
Mass：40916
Sequence：MPAHILQEISGAYSATTTITAPPSGGQQNGGEKFEKSSHHWGADVRPELKDDLYDPTYQDDEGPPPKLEYVWRNIILMALLHLGALYGITLVPSCKLYTCLFAYLYYVISALGITAGAHRLWSHRTYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFVLPTLVPWYCWGETFVNSLCVSTFLRYAVVLNATWLVNSAAHLYGYRPYDKNISSRENILVSMGAVGEGFHNYHHAFPYDYSASEYRWHINFTTFFIDCMALLGLAYDRKRVSRAAVLARIKRTGDGSCKSG
Tissue specificity：Detected in brain and skin (PubMed:10545940, PubMed:11161812, PubMed:16118274). Highly expressed in brain, and detected at low levels in heart, stomach, lung and testis (PubMed:11161812, PubMed:12815040). Detected both in dermis and epidermis (PubMed:16118274). {ECO:0000269|PubMed:10545940, ECO:0000269|PubMed:12815040, ECO:0000269|PubMed:16118274}.
Induction：Up-regulated by agonists that activate NR1H3 (PubMed:12815040). Slightly down-regulated by a high-carbohydrate diet enriched in unsaturated fatty acids (PubMed:12815040). {ECO:0000269|PubMed:12815040}.
Developmental stage：Highly expressed during embryonic development and during the first three weeks after birth. Expression is low in adults. {ECO:0000269|PubMed:16118274}.
Protein families：Fatty acid desaturase type 1 family