PRS28_MOUSE Q924N9
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UniProt:Q924N9
Recommended name:Serine protease 28
EC number:EC 3.4.21.-
Alternative names:(Implantation serine proteinase 1) (ISP-1) (Strypsin) (Tryptase-like proteinase)
Cleaved into:
GeneID:114661
Gene names (primary ):Prss28
Gene names (synonym ):Isp1
Gene names (ORF ):
Length:274
Mass:30628
Sequence:MFRLLLLALSCLESTVFMASVSISRSKPVGIVGGQRTPPGKWPWQVSLRMYSYEVNSWVHICGGSIIHPQWILTAAHCIQSQDADPAVYRVQVGEVYLYKEQELLNISRIIIHPDYNDVSKRFDLALMQLTALLVTSTNVSPVSLPKDSSTFDSTDQCWLVGWGNLLQRVPLQPPYQLHEVKIPIQDNKSCKRAYRKKSSDEHKAVAIFDDMLCAGTSGRGPCFGDSGGPLVCWKSNKWIQVGVVSKGIDCSNNLPSIFSRVQSSLAWIHQHIQ
Tissue specificity:Expressed in embryos throughout the preimplantation period, during blastocyst hatching and embryo outgrowth. Found in uterus especially in glandular epithelium. {ECO:0000269|PubMed:11425330, ECO:0000269|PubMed:12112596, ECO:0000269|PubMed:15293213}.
Induction:By progesterone.
Developmental stage:Highly expressed from 6.5 dpc in embryo plus deciduum. Faintly detectable at 11.5 dpc and 13.5 dpc in placenta. Not detected at 8.5 dpc, 11.5 dpc and 13.5 dpc in embryo proper. Expressed at 4.0 dpc in uterus. {ECO:0000269|PubMed:11425330, ECO:0000269|PubMed:15349836}.
Protein families:Peptidase S1 family