SDK1_MOUSE Q3UH53
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UniProt:Q3UH53
Recommended name：Protein sidekick-1
EC number：
Alternative names：
Cleaved into：
GeneID：330222
Gene names (primary )：Sdk1
Gene names (synonym )：
Gene names (ORF )：
Length：2193
Mass：240306
Sequence：MARARPSVAGGGVAAPPERAGPGRPRRSRTGHHCDPECPGLRAAPRTPGPGAGRRAAKLRPGRGWWALLLLQLHLLRALAQDDVAPYFKTEPGLPQIHLEGNRLVLTCLAEGSWPLEFKWIRNDSELTTYSSEYKYIIPSLQKLDAGFYRCVVRNRMGALLQRKSEIQVAYMGNFMDTDQRKTVSQGHAALLNLLPIVSCPQPQVTWFREGHKIIPSSRIAITLENQLVILATTASDAGAYYVQAVNEKNGENKTSPFIHLSVARDTGTHEAMAPIIVVAPGNRSVVAGSSETTLECIANARPVEELSVHWKRNGVRLTSGLHSYGRRLTITNPTSADTGMYVCEATLRGSTFEPARARAFLSIIEPPYFTAEPESRILGEVEETMDIPCRAMGVPLPTLQWYKDAVPLSKLQNPRYKVLPSGGLHIQKLSPEDSGIFQCFASNEGGEVQTHTYLDVTNIAPAFTQRPVDTTVTDGMTAVLRCEVSGAPKPAITWKRGNHILASGSVRIPRFMLLESGGLRIAPVFIQDAGNYTCYAANTEASVNASAMLTVWNRTSIVHPPEDRVVIKGTTATLCCGATHDPRTSLRYVWKKDNVVITASSSSRIVVEKDGSLVISQTWSGDIGDYTCEIISEGGSDSRTARLEVIELPHPPQNLLASLSPARSHSVTLSWVRPFDGNSPVLYYIVQVSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNQVGKGQYSTETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEHQQRNISSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQAEAVNSTTVHFLWNPPPQQFINGINQGYKLLAWPADAPETVTVVTIAPDFHGIHHGYITNLKKFTAYFTSVLCFTTPGDGPPSSPQLVWTHEDKPGAVGHLSFTEILDTSLKVSWQEPLERNGIIMGYQISWEVYGRNDSRLTHTLNSTMHEYKIQGLSSLTTYTIDVAALTAAGVGVTTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTAICRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMRQVNIVGPSPFSQSSRVIQTLQAPPDVAPTSLTVRTASETSLRLRWVPLPDSQYNGNPESVGYRVKYWRSDQPSSALAQVVSDRLERELTIEELEEWTEYELRMQAFNAIGAGPWSELVRGRTRESVPSAAPENVSAEAVSSTQILLTWASVPEQDQNGLILGYKVLYCAKDLDPEPRSHVVRGNHTQSALLAGLRKFVVYELQVLAFTRIGNGVPSSPLILERTKDDTPGPPVRLVFPEVRLTAVRIVWQPPEEPNGVILGYQIAYRLASGSPHTFTTVEVGATVRQFTATELAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTVQVRELPGGEWQTYSSSISHEATACAVERLRPFTSYKLRLKATNDIGDSDFSAETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELESETGMSPEPKTLKSPSALRAELTAQSSFKTVNSSSSLTTYELTHLKKYRRYEVIMTAYNIIGESPASVPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKVYYWEADSRNETEKMKVLFLPEPVVKIKDLTSHTKYLISISAFNAAGDGPKSDPCQGRTHQAAPGPPSFLAFSEITSTTLNVSWGEPSAANGILQGYRVVYEPLAPVQGVSKVVTVDVKGNWQRWLKVRDLTKGVTYFFRVQARTIAYGPELQANVTAGPAEGSPGSPRNVLVTKSASELTLQWTEGNAGTTPTTGYVIEARPSDEGLWDMFAKDIPRSATSYTVDLDKLRQGVTYEFRVVAVNKAGFGEPSRPSIAVSAQAEAPFYEEWWFLLVMALSSLLLILLVVFVLVLHGQSKKYKSCSTGKGISNMEETVTLDNGGFAALELNSRHLNVKSTFSKKNGTRSPPRPSPGGLHYSDEDICNKYNGAVLTESVNLKEKSVDGSESEASDSDYEEALPKHSFVNHYMSDPTYYNSWKRRPPAAAPHRYEAVAGAEAGPHLHTVITTQSAGGVYTPAGPGARAPLTGFSSFV
Tissue specificity：Expressed by non-overlapping subsets of retinal neurons. Sdk1 and Sdk2 are expressed in non-overlapping subsets of interneurons and retinal ganglion cells (RGCs) that form synapses in distinct inner plexiform layer (IPL) sublaminae (at protein level). {ECO:0000269|PubMed:26287463}.
Induction：
Developmental stage：Highly expressed in many fetal tissues, inlcuding kidney but shows markedly lower expression in adult organs. Expression in kidney is high throughout development with maximal expression occurring near birth. {ECO:0000269|PubMed:15213259}.
Protein families：Sidekick family