FRAS1_MOUSE Q80T14
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UniProt:Q80T14
Recommended name：Extracellular matrix protein FRAS1
EC number：
Alternative names：
Cleaved into：
GeneID：231470
Gene names (primary )：Fras1
Gene names (synonym )：Kiaa1500
Gene names (ORF )：
Length：4010
Mass：442369
Sequence：MGVLKAWLGVALALAEFAVLPNCEGACLYQGSFLADATIWKPDSCQNCRCHGDIVICKPVVCKNPRCAFEKGEVLWIAPNQCCPQCAPRTPGSCHHEGKIHEHGTEWASAPCTVCSCTHGEVRCSHQQCTPLSCGPQELEFLAEGRCCPICVGTGKPCSYDGHVFQDGEDWQLSRCAKCVCRNGLTQCFAAQCQPLFCNQDEIVVRVPGKCCSQCSARSCSTAGQVYEHGEQWKEDACTLCMCDQGQVRCHKQVCPPLRCAKGQGRARHHGQCCEECATPDRSCSSGGVLRYQDEMWKGSACEFCMCDQGQVTCQTGECAKVACALGEELVHLEGKCCPECISRNGYCIYEQKAETMSSSAREIKHVPDGEKWEEGPCKLCECREAQVTCYEPSCPPCPVATLALVVKGQCCPDCTPVHCHPDCLTCSHSPDHCDLCQDPTKLLQNGRCVHSCGLGFYQAGSLCLACQPQCSTCTNGLECSSCLPPLLMQQGQCVSTCGDGFYQDHHSCAVCHESCAGCWGPTEKHCMACRDPLQVLRDSSCENTCGNGFYNRQGTCVACDQSCKSCGPSSPRCLSCAEKTILHDGKCISECPHGYYADSTGSCKVCHSSCASCSGPTAAHCIACIHPQTLRQGHCLPSCGEGFYPDHGICEACHASCHTCVGPQPSHCTQCKKPEAGLLVEQHSGENVPYGKCVSRCGTHFYLESTGLCEVCHPSCLTCEGKSPHNCTGCESTHALLAGCCVSQCPETHFNLEGTCTECHPSCRQCHGPLESDCVSCHPHLTLTSGHCKTSCKEEQFLNLVGYCADCHPLCQHCVANLQDTGSICLKCQHARHLLLGDHCVPECPPGHYKERGTCKTCHSSCRSCQNGGPFSCSSCDTGLVLTHIGTCSTACFPGHYLDDNQVCQPCNRHCRSCDSQGSCTSCRDPSKVLLFGECQYESCTPQYYLDIATKTCKECDWSCNACTGPLRTDCLQCMDGYVLQDGVCVEQCSPQHYRDSGSCKRCDSHCVECQGPHECTRCEEPFLLFQAQCVQECGKGYFADHAKHRCIACPQGCLRCSHKDRCHLCDHSFFLKSGLCMPTCVPGFSGHSSNENCTDKMYTPSLHVNGSLTLGIGSMKPLDFSLLNIQHQDGRVEDLLFHVVSTPTNGQLLLSRNGKEVQLEKAGHFSWKDVNEKKVRFVHSKEKLRKGYFSLKISDQQFFSEPQLINIQAFSTQAPYVLRNEVLHVSKGERATITTQLLDIRDDDNPQDVVVNVLDPPLHGQLLQMPPAPAASIYQFHLDELSRGLLLYAHDGSDSTSDIIVFQANDGHSFQNILFHVKNIPKNDRALRLVTNSMVWVPEGGMLKITNRILKAQAPGVRADDIIYKITHSRPQFGEVVLLMNLPADSPAGPAEEGHHLPDGRMATPISTFTQQDIDDGVVWYRHLGAPTQSDSFRFQVSSATSAQEHLESHMFNIAILPQAPEAPKLSLGTSLHMTAREDGLSVIQPQSLSFVKAESPSGKIIYNITVPLHPNQGIIEHRDRPHSPIQYFTQEDINQGQIMYRPPVAPPHLQEIMAFSFAGLPESVKFYFTVSDGQHTSPEMALTIHLLHSDLQPPAFQVKAPLLEVSPGGRTSLGLQLLVRDAQVVPEELFFQLQKSPQHGMLVKYTAKSSVTMAAGDTFTYDEVERNVLQYVHDGSSAWEDSLEISVTDGLTVTTSEVKVEVSPSENRGPRLAPGSSLSMTVASQHTAIITRSHLAYVDDSSSDPEIWIRLSSLPLYGVLFRSSGPDMDELSGDSNFTMEDINKKNIRYSAVFETDGHSVTDGFHFSVSDMDGNHVDNQVFTITVTPAENPPHIIAFADLITVDEGGRAPLSLHHFFATEDQDNLQDDAVIKLSALPKYGCIENTGTGDRFGPGANSELEASFPIQDVLENYIYYFQSVHESIEPTHDVFSFYVSDGSGRSEIHSINITIERKNDEPPRMTLRPLGVRLSSGVAISNSSLSLQDLDTPDNELIFVLMKKPDHGHLLRRSTASDPLENGTVLDQGSSFTYQDVLAGLVGYLPGDIYMAVDEFRFSLTDGLHVDTGRMEIYIELPSTNIPHLAINRGLQLSAGSVARITEQHLKATDTDSEAGQVVYIMKEDPGAGRLLMAKADNLEQISVRGPIRSFTQADVSQGQIEYSHGPGEPGGSFAFKFDVVDGEGNKLADQSFSIGVLEDKSPPVVITNRGLVLDENSVEKITTAQLSATDQDSKPTELIYRITTQPQLGHLEHVASPGIQISSFTQADLASRNVQYVRSSGTGKQSDAFSFVLSDGLHEVTQTFPITIHPVDDARPLVQNRGMRVQEGVRKTITEFELKAVDVDTEAESITFTIVQPPRHGTIERTARGQRFHQTSSFTMEDIYQNRVSYSHDGSNSLKDRFTFTVSDGTNPFFIIEEGGEEIMTAAPQQFHVDILPVDDGTPRIVTNLGLQWLEYMDGKATNLITKKELLTVDPDTEDSQLIYEVTTGPMHGYLENKLQPGRAAATFTQEHVNLGLIRYVLYEEKIQKVMDSFQFLVKDSKPNVVSDNVFHIQWSLISFKYTSYNVSEKAGSVSVTVQRTGNLNQYAIVLCRTEQGTASSSSHPGQQDYMEYAGQVQFDEGEGTKSCTVIINDDDVFENIESFTVGLSMPAYALLGEFTQAKVVINDTEDEPTLEFDKKTYRVNESAGFLFAPIKRQGDSSSTVSAVCYTVPKSAMGSSLYALESGSDFKSRGRSAESRVIFGPGVTVSTCDVMVIDDSEYEEEEEFEIALADASNNARIGRQAVAKVLISGPNDASTVSLGNTAFTISEDAGTVKIPVIRHGTDLSTFTSVWCATRPSDPASATPGVDYVPSSRKVEFGPGITEQYCTLTILDDTQYPVIEGLETFVVFLSSAQGAELTKPSQAVIAINDTFQDVPSMQFSKDLLLVKEKEGVLHIPIIRSGDLSYESSVRCYTQGHSAQVMEDFEERRNADSSRITFLKGQKTKNCTVYIHDDSMFEPEEQFRVYLGHPLGNHWSGARIGKNSVATVTISNDEDAPTIEFEEAAYQVREPAGPEAIAVLSIKVIRRGDQNRTSKIRCSTRDGSAQSGVDYYPKSRVLKFSPGVDHIFFKVEILSNEDREWHESFSLVLGPDDLVEAVLGDVTTATVTILDQEAAGSLILPAPPIVVTLADYDHVEELAKEGVKKAPSPGYPLVCVTPCDPRYPRYAVMKERCSEAGINQTSVQFSWEVAAPTDGNGARSPFETITDNTPFTSVNHKVLDSIYFSRRFHVRCVAKAVDKVGHVGTPLRSNVVTIGTDSAICHTPVVAGTARGFQAQSFIATLKYLDVKHKEHPNRIHISVQIPHQDGMLPLISTMPLHNLHFLLSESIYRHQHVCSNLVTAQDLRGLAEAGFLNDAGFHSTALGPGYDRPFQFDSSVREPKTIQLYRHLNLKSCVWTFDAYYDMTELIDVCGGSVTADFQVRDSAQSFLTVHVPLYVSYIYVTAPRGWASLEHHTEMEFSFFYDTVLWRTGIQTDSVLSARLQIIRIYIREDGRLVIEFKTHAKFRGQFVIEHHTLPDVKSFILTPDHLGGIQFDLQLLWSAQTFDSPHQLWRATSSYNRKDYSGEYTIYLIPCTVQPTQPWVDPGEKALACTAHAPERFLIPIAFQQTNRPVPVVYSLNTEFQLCNNEKVFLMDPNTSDMSLAEMDYKGAFSKGQILYGRVLWNPEQNLHSAYKLQLEKVYLCTGKDGYVPFFDPTGTIYNEGPQYGCIQPNKHLKHRFLLLDRSQPEVTDKYFHDVPFEAHFASELPDFQVVSSMPGVDGFTLKVDALYKVEAGHQWYLQVIYIIGPDSTSRPRVQRSLTVSLRRHQRDLVDPSGWLSLDDSLIYDNEGDQVKNGTNMKSLNLEMQEPVIAASLSQTGASIGSALAAIMLLLLLFLVACFVTRKCQKQKKKQPPEDTLEEYPLNTKVDVAKRNADKVEKNANRQYCTVRNVNILSDNEGYYTFKGAKVKKLNLEVRVHNNLQDGTEV
Tissue specificity：Found in a linear fashion underlying the epidermis and the basal surface of other epithelia in embryos. {ECO:0000269|PubMed:12766770}.
Induction：
Developmental stage：Highly expressed in the apical ectodermal ridge of the limb buds from 10.5-12.5 dpc and expression was also detected in the interdigital spaces at 14.5 dpc. Found in cells just underlying the surface epithelium of the entire embryo and in the linings of the peritoneal cavity and dorsal aorta. At 12 dpc, detected in the mesonephric duct and in the lens. {ECO:0000269|PubMed:12766769}.
Protein families：FRAS1 family