BASI_MOUSE P18572
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UniProt:P18572
Recommended name：Basigin
EC number：
Alternative names：(Basic immunoglobulin superfamily) (HT7 antigen) (Membrane glycoprotein gp42) (CD antigen CD147)
Cleaved into：
GeneID：12215
Gene names (primary )：Bsg
Gene names (synonym )：
Gene names (ORF )：
Length：389
Mass：42445
Sequence：MAAALLLALAFTLLSGQGACAAAGFLKAPLSQERWAGGSVVLHCEAVGSPIPEIQWWFEGNAPNDSCSQLWDGARLDRVHIHAAYRQHAASSLSVDGLTAEDTGTYECRASSDPDRNHLTRPPRVKWVRAQASVVVLEPGTIQTSVQEVNSKTQLTCSLNSSGVDIVGHRWMRGGKVLQEDTLPDLHTKYIVDADDRSGEYSCIFLPEPVGRSEINVEGPPRIKVGKKSEHSSEGELAKLVCKSDASYPPITDWFWFKTSDTGEEEAITNSTEANGKYVVVSTPEKSQLTISNLDVNVDPGTYVCNATNAQGTTRETISLRVRSRMAALWPFLGIVAEVLVLVTIIFIYEKRRKPDQTLDEDDPGAAPLKGSGTHMNDKDKNVRQRNAT
Tissue specificity：[Isoform 1]: Retina-specific (PubMed:12939332, PubMed:11273674, PubMed:11853760, PubMed:25957687). Expressed in both rods and cones (at protein level) (PubMed:25957687). {ECO:0000269|PubMed:11273674, ECO:0000269|PubMed:11853760, ECO:0000269|PubMed:12939332, ECO:0000269|PubMed:25957687}.; [Isoform 2]: Testis and caput, corpus and cauda epididymides (at protein level) (PubMed:11882021, PubMed:23727514, PubMed:21792931). Expressed in the brain, lung, liver, kidney, heart, spleen, uterus, retina and skeletal muscle (PubMed:2361961, PubMed:12939332, PubMed:12601063). {ECO:0000269|PubMed:11882021, ECO:0000269|PubMed:12601063, ECO:0000269|PubMed:12939332, ECO:0000269|PubMed:21792931, ECO:0000269|PubMed:2361961, ECO:0000269|PubMed:23727514}.
Induction：By estrogen in the uterine epithelium of ovariectomized animals. By eCG in ovary. {ECO:0000269|PubMed:12211060, ECO:0000269|PubMed:15095333}.
Developmental stage：In developing eye expressed at embryonic days 12 dpc, 15 dpc and 18 dpc, and at postnatal days P1, P7, P14, and P21. Expression progressed from a more generalized distribution throughout the undifferentiated neural retina to specific staining of retina-pigmented epithilia, the MCs, photoreceptor cells and the ciliary apparatus. Expression is highest at P21. Isoform 1 and isoform 2 are expressed at equivalent levels at P7, isoform 1 is more abundant at P14, P21 and P28. In uterus during the peri-implantation period strongly expressed in luminal and glandular epithelium on day 1 of pregnancy and gradually decreased to a basal level from day 2-4 of pregnancy. Expression in the sub-luminal stroma was first detected on day 3 of pregnancy and increased on day 4 of pregnancy. On day 5 of pregnancy, the expression of basigin protein and mRNA was only detected in the implanting embryos, and the luminal epithelium and sub-luminal stroma surrounding the embryos. In ovary during sexual maturation expressed in the granulosa cells of preantral follicles at days 20 and 25 after birth. Expressed during corpus luteum formation. {ECO:0000269|PubMed:12211060, ECO:0000269|PubMed:15037112, ECO:0000269|PubMed:15095333}.
Protein families：