KCC1D_MOUSE   Q8BW96


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UniProt:Q8BW96

Recommended name:Calcium/calmodulin-dependent protein kinase type 1D

EC number:EC 2.7.11.17

Alternative names:(CaM kinase I delta) (CaM-KI delta) (CaMKI delta) (CaM kinase ID) (CaMKI-like protein kinase) (CKLiK) (mCKLiK)

Cleaved into:

GeneID:227541

Gene names  (primary ):Camk1d

Gene names  (synonym ):

Gene names  (ORF ):

Length:385

Mass:42919

Sequence:MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALSKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRRLQLGSSLDSSNASVSSNLSLASQKDCLAPSTLCSFLSSSSGVAGVGAERRPRPTTVTTGHTGSK

Tissue specificity:Expressed ubiquitously with high levels in brain and low levels in kidney. Isoform 2 is highly expressed in brain compared to other tissues. In hematopoietic cell lines predominant expression was detected in T and EC cells. {ECO:0000269|PubMed:14980499}.

Induction:Down-regulated upon cholesterol-rich diet. {ECO:0000269|PubMed:12897189}.

Developmental stage:In EML cell line differentiation, expression increases 4 to 8 hours after treatment with all-trans retinoic acid (ATRA) and then declines after 24 hours of ATRA induction. {ECO:0000269|PubMed:18400360}.

Protein families:Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily


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