K1C15_MOUSE Q61414
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UniProt:Q61414
Recommended name：Keratin, type I cytoskeletal 15
EC number：
Alternative names：(Cytokeratin-15) (CK-15) (Keratin-15) (K15)
Cleaved into：
GeneID：16665
Gene names (primary )：Krt15
Gene names (synonym )：Krt1-15
Gene names (ORF )：
Length：452
Mass：49138
Sequence：MATTFLQTSSTFGGSSTRGASLRAGGGSFGGGSLYGGGGSRSISASSARFVSSGAGGGFGGGMSCGFGGGFGGGFGGGFGGGFGDFGGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEQANTELEVKIRDWYQKQSPASPDRDYSHYFKTMEEIRDKILAATIDNSRVVLEIDNARLAADDFRLKYENELTLRQGVEADINGLRRVLDELTLARTDLEMQIEQLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTLQGLEIELQSQLSMKAGLENSLAEVECRYATQLQQIQGVITGLETQLSELRCEMEAQNQEYNMLLDIKTRLEQEIATYRNLLEGQDAKMAGIGVREGSSGGGGSSSSSSNFHISVEESVDGKVVSSRKREI
Tissue specificity：Expressed strongly in the basal cell layer at the tips of rete-like prominences (RLPs) of adult dorsal tongue, outer root sheath (ORS) of hair follicle and skin epidermis (at protein level). {ECO:0000269|PubMed:10623468, ECO:0000269|PubMed:14506658}.
Induction：During wound healing expression is suppressed by TGF-beta, TNF-alpha and to a lesser extent by epidermal and keratinocyte growth factors (EGF and KGF respectively). {ECO:0000269|PubMed:10623468}.
Developmental stage：In neonatal mice, additional expression seen in the basal layer of the cornea, forestomach and esophagus (at protein level). {ECO:0000269|PubMed:7539810}.
Protein families：Intermediate filament family