PROK1_MOUSE Q14A28
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UniProt:Q14A28
Recommended name：Prokineticin-1
EC number：
Alternative names：(Endocrine-gland-derived vascular endothelial growth factor) (EG-VEGF)
Cleaved into：
GeneID：246691
Gene names (primary )：Prok1
Gene names (synonym )：Pk1
Gene names (ORF )：
Length：105
Mass：11678
Sequence：MRGAVHIFIMLLLATASDCAVITGACERDIQCGAGTCCAISLWLRGLRLCTPLGREGEECHPGSHKIPFLRKRQHHTCPCSPSLLCSRFPDGRYRCFRDLKNANF
Tissue specificity：Highly expressed in liver and ovary and weakly expressed in testis and placenta. Expressed in mucosa and mesenchyme of embryonic gut during enteric nervous system development (at protein level). Predominantly expressed in kidney and liver. Also expressed in lung, ovary, placenta and testis. In fetal liver, is restricted to and highly expressed in hepatocytes. In adult kidney, expression is restricted to the endothelial tubule cells. In placenta, expressed throughout gestation. {ECO:0000269|PubMed:12746324, ECO:0000269|PubMed:17324478, ECO:0000269|PubMed:17531315}.
Induction：
Developmental stage：In placenta, at 7.5 dpc highly expressed in ectoplacental cone, endoderm and in giant cells, and at 9.5 dpc restricted mainly to the labyrinth layer (at protein level). In placenta, most highly expressed during early gestation (between 9.5 and 10.5 dpc). {ECO:0000269|PubMed:17531315}.
Protein families：AVIT (prokineticin) family