DMC1_MOUSE Q61880
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UniProt:Q61880
Recommended name:Meiotic recombination protein DMC1/LIM15 homolog
EC number:
Alternative names:
Cleaved into:
GeneID:13404
Gene names (primary ):Dmc1
Gene names (synonym ):Dmc1h Lim15
Gene names (ORF ):
Length:340
Mass:37821
Sequence:MKEDQVVQEESGFQDDEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSERRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGTGGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE
Tissue specificity:Testis. {ECO:0000269|PubMed:30760716, ECO:0000269|PubMed:8581742}.
Induction:
Developmental stage:In spermatocytes, shows punctate localization along chromosome axes specifically in early meiotic prophase I cells. Foci start to appear from the leptotene stage, reach their greatest number in the zygotene stage, in the early pachytene stage, the DMC1 foci mostly disappeared from autosomes and became restricted to the sex chromosomes. {ECO:0000269|PubMed:30760716}.
Protein families:RecA family, DMC1 subfamily