RIOX2_MOUSE Q8CD15
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UniProt:Q8CD15
Recommended name：Ribosomal oxygenase 2
EC number：EC 1.14.11.-
Alternative names：(Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA) (Histone lysine demethylase MINA) (MYC-induced nuclear antigen)
Cleaved into：
GeneID：67014
Gene names (primary )：Riox2
Gene names (synonym )：Mina Mina53
Gene names (ORF )：
Length：465
Mass：53517
Sequence：MPKKVQPTGDENEEASVPCKRVKEELPETLSVLNFDSPSSFFESLISPIKVETFFKEFWEQKPLLIQRDDPVLAKYYQSLFSLSDLKRLCKKGVYYGRDVNVCRSISGKKKVLNKDGRAHFLQLRKDFDQKRATIQFHQPQRYKDELWRIQEKLECYFGSLVGSNVYMTPAGSQGLPPHYDDVEVFILQLEGTKHWRLYSPTVPLAHEYSVESEDRIGTPTHDFLLKPGDLLYFPRGTIHQAETPSGLAYSIHLTISTYQNNSWGDCLLDSISGFVFDIAKEDVALRSGMPRRMLLNVETPADVTRKLSGFLRTLADQLEGREELLSSDMKKDFVKHRLPPFFEGNGTETMDPGKQLPRLDNIIRLQFKDHIVLTVGPDKNPFDEAQQKVVYIYHSLKNVRQMHMIGEEEESEIFGLRFPLSHVDALKQIWCGSPIRVKDLKLDTDEEKENLALSLWSESLIQVL
Tissue specificity：Predominantly expressed in testis. Expressed at high levels in spleen, thymus, and colon, but barely detectable in brain, skeletal muscle, and seminal vesicle (at protein level). {ECO:0000269|PubMed:16533354}.
Induction：Up-regulated in experimentally-induced cryptorchid testis. {ECO:0000269|PubMed:16533354}.
Developmental stage：In testis, expressed in the nuclei of spermatogonia at all stages of the seminiferous epithelial cycle, and in meiotic prophase cells such as preleptotene, leptotene and zygotene, and weakly in early pachytene spermatocytes, but is absent in late pachytene spermatocytes, spermatids and mature sperm (at protein level). {ECO:0000269|PubMed:16533354}.
Protein families：ROX family, MINA53 subfamily