SRMS_MOUSE Q62270
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UniProt:Q62270
Recommended name：Tyrosine-protein kinase Srms
EC number：EC 2.7.10.2
Alternative names：(PTK70)
Cleaved into：
GeneID：
Gene names (primary )：Srms
Gene names (synonym )：Srm
Gene names (ORF )：
Length：496
Mass：55758
Sequence：MEPFLRKRLTFLSFFWDKIWPADESEEDIPRIQGHDDNPVPEQAAAVEPCSFPAPRARLFRALYDFTARCAEELSVSRGDRLYALKEEGDYIFAQRLSGPPSTGLVPVTYLAKATPEPPSDQPWYFSGISRAQAQQLLLSPANAPGAFLIRPSESSIGGYSLSVRAQAKVCHYRICMAPSGSLYLQEGQLFPSLDALLAYYKTNWKLIQNPLLQPCIPQIPLVQDEWERPRSEFVLRRKLGEGFFGEVWEGLWLGSIPVAVKVIKSADMKLADLTKEIEALKSLRHERLIRLHAICSLGEPVYIVTELMGKGNLQVYLGSSEGKALSLPHLLGFACQVAEGMSYLEERRVVHRDLAARNVLVGDDLTCKVADFGLARLLKDDVYSPSSGSKIPVKWTAPEAANYRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTNHETLQQISRGYRLPRPAVCPAEVYVLMVECWKGSPEERPTFAILREKLNAINRRLHLGLT
Tissue specificity：Higher expression in liver, lung, thymus and skin than in brain, kidney, heart and spleen (PubMed:9226137). In skin, highly expressed in keratinocytes (PubMed:9226137). Abundant in lung, liver, spleen, kidney and testis and is also detected in the cerebrum (PubMed:7935409). {ECO:0000269|PubMed:7935409, ECO:0000269|PubMed:9226137}.
Induction：
Developmental stage：In the brain, expression is low at 11 dpc with higher levels detected in 15 dpc and postnatal brain. Expressed at low levels in adult brain. {ECO:0000269|PubMed:7935409}.
Protein families：Protein kinase superfamily, Tyr protein kinase family, SRC subfamily