DTX3_MOUSE Q80V91
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UniProt:Q80V91
Recommended name:Probable E3 ubiquitin-protein ligase DTX3
EC number:EC 2.3.2.27
Alternative names:(Protein deltex-3) (Deltex3) (mDTX3) (RING-type E3 ubiquitin transferase DTX3)
Cleaved into:
GeneID:80904
Gene names (primary ):Dtx3
Gene names (synonym ):
Gene names (ORF ):
Length:347
Mass:37982
Sequence:MSFVLSRMAACGGSCKNKVTVSKPVWDFLSKETPARLARLREEHRVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKAQRQGELMGCLALGGGGEHPELHRPGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREDAEEQETTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD
Tissue specificity:Strongly expressed in testis and brain. Weakly expressed in kidney. {ECO:0000269|PubMed:11226752}.
Induction:
Developmental stage:In the CNS, it is expressed in the developing neural tube starting from 10.5 dpc in the spinal cord and around 11.5 dpc in the telencephalon. Expressed ubiquitously throughout the spinal cord and telencephalon during neurogenesis. Expressed throughout the developing retina at 15.5 dpc. Not expressed in the somite or presomite during somitogenesis. Expressed slightly later that Dtx2. {ECO:0000269|PubMed:11226752}.
Protein families:Deltex family