MFRN1_MOUSE   Q920G8


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UniProt:Q920G8

Recommended name:Mitoferrin-1

EC number:

Alternative names:(Mitochondrial iron transporter 1) (Mitochondrial solute carrier protein) (Solute carrier family 25 member 37)

Cleaved into:

GeneID:67712

Gene names  (primary ):Slc25a37

Gene names  (synonym ):Mfrn Mscp

Gene names  (ORF ):

Length:338

Mass:37510

Sequence:MELRRGGVGNQAAGRRMDGDCRDGGCGSKDAGSEDYENLPTSASVSTHMTAGAMAGILEHSIMYPVDSVKTRMQSLNPDPKARYTSIYGALKRIMHTEGFWRPLRGLNVMMMGAGPAHAMYFACYENMKRTLNDVFSHQGNSHLANGVAGSMATLLHDAVMNPAEVVKQRLQMYNSQHQSAFSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPRRDYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYILTKRQLENRTLY

Tissue specificity:Highly expressed in hematopoietic organs, fetal liver, bone marrow and spleen. {ECO:0000269|PubMed:11845285, ECO:0000269|PubMed:16511496}.

Induction:

Developmental stage:In the developing embryo, it is first detected at 7.5 dpc in the extraembryonic yolk sac, coincident with the appearance of blood islands. Later, restricted expression is seen in 14.5 dpc fetal liver, the primary source of erythrocyte production in mid-gestation. Expression decreases in the spleen around 4-5 weeks of age, suggesting that it is decreased during splenic lymphocyte maturation. {ECO:0000269|PubMed:16511496}.

Protein families:Mitochondrial carrier (TC 2.A.29) family


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