KRA14_MOUSE   O08640


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UniProt:O08640

Recommended name:Keratin-associated protein 14

EC number:

Alternative names:(Anagen-specific protein KAP13) (mKAP13) (Pubertal mammary gland-specific protein 1)

Cleaved into:

GeneID:23927

Gene names  (primary ):Krtap14

Gene names  (synonym ):Pmg1

Gene names  (ORF ):

Length:167

Mass:17919

Sequence:MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF

Tissue specificity:Expressed at high levels in skin where it is found predominantly in the keratogenous zone of hair follicle cortical cells and at lower levels in the epithelium of the developing mammary gland. {ECO:0000269|PubMed:10446281, ECO:0000269|PubMed:9287118, ECO:0000269|PubMed:9804342}.

Induction:

Developmental stage:In the developing mammary gland, expression is barely detected in the immature gland at 3 weeks after birth but is evident at the onset of puberty at 3.5 weeks. Expression is high at 4 weeks, declines at 4.5 weeks and is undetectable at 5 weeks. No expression is detected in the mature mammary gland during estrus, pregnancy, lactation or involution. In skin, expression starts shortly after birth and reaches a first maximum at 9 days. A second peak of expression is observed at 3.5 weeks, then levels decline and remain low in the adult. During the hair growth cycle, detected in mid- and late-anagen stages but not in catagen, telogen or early anagen phases. {ECO:0000269|PubMed:10446281, ECO:0000269|PubMed:9287118, ECO:0000269|PubMed:9804342}.

Protein families:PMG family


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