ZDH21_MOUSE   Q9D270


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UniProt:Q9D270

Recommended name:Palmitoyltransferase ZDHHC21

EC number:EC 2.3.1.225

Alternative names:(DHHC domain-containing cysteine-rich protein 21) (DHHC21) (GABA-A receptor-associated membrane protein 3) (Zinc finger DHHC domain-containing protein 21)

Cleaved into:

GeneID:68268

Gene names  (primary ):Zdhhc21

Gene names  (synonym ):Gramp3

Gene names  (ORF ):

Length:265

Mass:31331

Sequence:MGLRIHFVVDPHGWCCMGLIVFVWLYNIVIIPKIVLFPHYEEGHIPGILIIIFYGISIFCLVALVRASLTDPGRLPENPKIPHAERELWELCNKCNLMRPKRSHHCSRCGHCVRRMDHHCPWINNCVGEDNHWLFLQLCFYTELLTCYALMFSFCHYYYFLPLKKRNLDLFVVRHELAIMRLAAFMGITMLVGITGLFYTQLIGIITDTTSIEKMSNCCEEISRPRKPWQQTFSEVFGTRWKILWFIPFRQRQPLRVPYHFANHV

Tissue specificity:Widely expressed (PubMed:26715683). Expressed in Henle's layer within the hair bulb and the hair shaft cuticle (at protein level) (PubMed:19956733). Expression is limited to the post-mitotic lineages of inner root sheath (IRS) and cuticle (PubMed:19956733). {ECO:0000269|PubMed:19956733, ECO:0000269|PubMed:26715683}.

Induction:

Developmental stage:In the developing skin, expression is not be detected prior to hair follicle induction (13 dpc). Expression is initially detected in the inner root sheath (IRS) of developing vibrissae follicles at 16 dpc and later in the developing IRS of E18.5 pelage follicles. {ECO:0000269|PubMed:19956733}.

Protein families:DHHC palmitoyltransferase family


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