HM13_MOUSE Q9D8V0
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UniProt:Q9D8V0
Recommended name:Minor histocompatibility antigen H13
EC number:EC 3.4.23.-
Alternative names:(Presenilin-like protein 3) (Signal peptide peptidase)
Cleaved into:
GeneID:14950
Gene names (primary ):Hm13
Gene names (synonym ):H13 Psl3
Gene names (ORF ):
Length:378
Mass:41748
Sequence:MDSAVSDPHNGSAEAGTPANGTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARGKSSSDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPANFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSVVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVAEMFSYEESNPKDPAAETESKEESTEASASKRLEKKEK
Tissue specificity:Widely expressed with highest levels in liver and kidney. In the brain, expressed predominantly in hippocampus, amygdala, piriform cortex, choroid plexus and arcuate nucleus of the hypothalamic area. Isoform 1 is more strongly expressed than isoform 4 in most tissues except brain and skeletal muscle where isoform 4 is the dominant isoform and in testis where isoform 1 and isoform 4 are expressed at similar levels. In the brain, isoform 4 is not detected in the choroid plexus. {ECO:0000269|PubMed:12972007, ECO:0000269|PubMed:16730383}.
Induction:
Developmental stage:In the embryo, expression starts at day 6.5. {ECO:0000269|PubMed:12972007}.
Protein families:Peptidase A22B family