HM13_MOUSE   Q9D8V0


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UniProt:Q9D8V0

Recommended name:Minor histocompatibility antigen H13

EC number:EC 3.4.23.-

Alternative names:(Presenilin-like protein 3) (Signal peptide peptidase)

Cleaved into:

GeneID:14950

Gene names  (primary ):Hm13

Gene names  (synonym ):H13 Psl3

Gene names  (ORF ):

Length:378

Mass:41748

Sequence:MDSAVSDPHNGSAEAGTPANGTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARGKSSSDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPANFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSVVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVAEMFSYEESNPKDPAAETESKEESTEASASKRLEKKEK

Tissue specificity:Widely expressed with highest levels in liver and kidney. In the brain, expressed predominantly in hippocampus, amygdala, piriform cortex, choroid plexus and arcuate nucleus of the hypothalamic area. Isoform 1 is more strongly expressed than isoform 4 in most tissues except brain and skeletal muscle where isoform 4 is the dominant isoform and in testis where isoform 1 and isoform 4 are expressed at similar levels. In the brain, isoform 4 is not detected in the choroid plexus. {ECO:0000269|PubMed:12972007, ECO:0000269|PubMed:16730383}.

Induction:

Developmental stage:In the embryo, expression starts at day 6.5. {ECO:0000269|PubMed:12972007}.

Protein families:Peptidase A22B family


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