MACOI_MOUSE Q7TQE6
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UniProt:Q7TQE6
Recommended name：Macoilin
EC number：
Alternative names：(Brain-specific adapter protein C61) (Macoilin-1) (Transmembrane protein 57)
Cleaved into：
GeneID：66146
Gene names (primary )：Maco1
Gene names (synonym )：Tmem57
Gene names (ORF )：
Length：664
Mass：76089
Sequence：MKRRNADCSKLRRPLKRNRITEGIYGSTFLYLKFLVVWALVLLADFVLEFRFEYLWPFWLFIRSVYDSFRYQGLAFSVFFVCVAFTSNIICLLFIPIQWLFFAASTYVWVQYVWHTERGVCLPTVSLWILFVYIEAAIRFKDLKNFHVDLCRPFAAHCIGYPVVTLGFGFKSYVSYKMRLRKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKGPSAHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISALSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRSRIRELEAEGKKLTMDMKVKEEQIRELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSITYSAATSPLSPVSPHYSSKFVETSPSGLDPNASVYQPLKK
Tissue specificity：Strong expression in whole nervous system up to 12.5 dpc. Highly expressed in all neuronal differentiation fields from 14.5 dpc to birth, with highest expression in the telencephalic cortical plate and mitral cells in the olfactory bulb, and lower expression in neuronal progenitor zones. Progressively decreased expression in fields of neuron precursor proliferation from 14.5 dpc and virtually undetectable there by 17.5 dpc. No significant expression detected outside the nervous system. After birth, significant expression remains in the cerebellum, olfactory bulb and hippocampus. {ECO:0000269|PubMed:15255972}.
Induction：
Developmental stage：In the embryo, stronger expression at 15.5 dpc than at 10.5 dpc or 19.5 dpc. Expression decreases after birth although significant expression remains associated with some neuronal structures at P10. {ECO:0000269|PubMed:15255972}.
Protein families：Macoilin family