G6PC2_MOUSE Q9Z186
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UniProt:Q9Z186
Recommended name：Glucose-6-phosphatase 2
EC number：EC 3.1.3.9
Alternative names：(G-6-Pase 2) (G6Pase 2) (Islet-specific glucose-6-phosphatase catalytic subunit-related protein)
Cleaved into：
GeneID：14378
Gene names (primary )：G6pc2
Gene names (synonym )：Igrp
Gene names (ORF )：
Length：355
Mass：40681
Sequence：MDFLHRSGVLIIHHLQEDYRTYYGFLNFMSNVGDPRNIFSIYFPLWFQLNQNVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWIQETEIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALSYTISRMEESSVTLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGVHMASLSVYLKTNVFLFLFALGFYLLLRLFGIDLLWSVPIAKKWCANPDWIHIDSTPFAGLVRNLGVLFGLGFAINSEMFLRSCQGENGTKPSFRLLCALTSLTTMQLYRFIKIPTHAEPLFYLLSFCKSASIPLMVVALIPYCVHMLMRPGDKKTK
Tissue specificity：Specifically expressed in pancreatic islet cells, in particular those of beta-cell origin. Not detected in testis, kidney, muscle, liver, lung, spleen, brain, pituitary, gastric fundus or heart. {ECO:0000269|PubMed:10078553, ECO:0000269|PubMed:12878201, ECO:0000269|PubMed:14722102}.
Induction：Up-regulated in islet cells cultured in hyperglycemic concentrations of glucose. {ECO:0000269|PubMed:14722102}.
Developmental stage：Initial onset of expression in the pancreas is at 12 dpc and prominent expression is detected at 14 dpc. {ECO:0000269|PubMed:10078553}.
Protein families：Glucose-6-phosphatase family