PORCN_MOUSE Q9JJJ7
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UniProt:Q9JJJ7
Recommended name:Protein-serine O-palmitoleoyltransferase porcupine
EC number:EC 2.3.1.250
Alternative names:(mPORC) (EC 2.3.1.250)
Cleaved into:
GeneID:53627
Gene names (primary ):Porcn
Gene names (synonym ):Porc Ppn
Gene names (ORF ):
Length:461
Mass:52508
Sequence:MATFSRQEFFQQLLQGCLLPTVQQGLDQIWLLLTICFACRLLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVAMKAVSLGFDLDRGEVGAVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSRRWLKKVARSLALALLCLVLSTCVGPYLFPYFIPLDGDRLLRNKKRKARGTMVRWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSRPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLAQILSACILSKRCLPDCSHRHRLGLGVRALNLLFGALAIFHLSYLGSLFDVDVDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
Tissue specificity:Expressed in brain, heart, kidney, liver, lung, muscle, spleen and testis. Isoform 4 is strongly expressed in kidney, liver, lung, spleen and testis. Isoform 1 is strongly expressed in brain, heart and muscle and poorly in kidney, liver, lung, spleen and testis. {ECO:0000269|PubMed:10866835}.
Induction:
Developmental stage:Isoform 1, isoform 2, isoform 3 and isoform 4 are expressed at different levels in embryo at 9.5, 10.5, 11.5, 12.5, 13.5 and 15.5 dpc. {ECO:0000269|PubMed:10866835}.
Protein families:Membrane-bound acyltransferase family, Porcupine subfamily