PORCN_MOUSE   Q9JJJ7


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UniProt:Q9JJJ7

Recommended name:Protein-serine O-palmitoleoyltransferase porcupine

EC number:EC 2.3.1.250

Alternative names:(mPORC) (EC 2.3.1.250)

Cleaved into:

GeneID:53627

Gene names  (primary ):Porcn

Gene names  (synonym ):Porc Ppn

Gene names  (ORF ):

Length:461

Mass:52508

Sequence:MATFSRQEFFQQLLQGCLLPTVQQGLDQIWLLLTICFACRLLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVAMKAVSLGFDLDRGEVGAVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSRRWLKKVARSLALALLCLVLSTCVGPYLFPYFIPLDGDRLLRNKKRKARGTMVRWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSRPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLAQILSACILSKRCLPDCSHRHRLGLGVRALNLLFGALAIFHLSYLGSLFDVDVDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG

Tissue specificity:Expressed in brain, heart, kidney, liver, lung, muscle, spleen and testis. Isoform 4 is strongly expressed in kidney, liver, lung, spleen and testis. Isoform 1 is strongly expressed in brain, heart and muscle and poorly in kidney, liver, lung, spleen and testis. {ECO:0000269|PubMed:10866835}.

Induction:

Developmental stage:Isoform 1, isoform 2, isoform 3 and isoform 4 are expressed at different levels in embryo at 9.5, 10.5, 11.5, 12.5, 13.5 and 15.5 dpc. {ECO:0000269|PubMed:10866835}.

Protein families:Membrane-bound acyltransferase family, Porcupine subfamily


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