ITA7_MOUSE Q61738
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UniProt:Q61738
Recommended name：Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain]
EC number：
Alternative names：
Cleaved into：
GeneID：
Gene names (primary )：Itga7
Gene names (synonym )：
Gene names (ORF )：
Length：1179
Mass：129329
Sequence：MARIPRCDFLRPPGIYYLITSLLAGLFLPPAIAFNLDVMGAIRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDRGANVQKESKENQWLGVSVRSQGAGGKIVTCAHRYESRQRVDQALETRDVIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAATFSPDSHYLVFGAPGTYNWKGTARVELCAQGSPDLAHLDDGPYEAGGEKEQDPRLIPVPANSYLGLLFVTNIDSSDPDQLVYKTLDPADRLTGPAGDLTLNSYLGFSIDSGKGLMRSEELSFVAGAPRANHKGAVVILRKDSATRLIPEVVLSGERLTSGFGYSLAVTDLNNDGWADLIVGAPYFFERQEELGGAVYVYMNQGGHWADISPLRICGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVVKPSQVLEGEAVGIKSFGYSLSGGLDVDGNHYPDLLVGSLADTAALFRARPVLHVSQEIFIDPRAIDLEQPNCADGRLVCVDIKICFSYVAVPSSYSPSVALDYMLDGDTDRRLRGQVPRVTFLSRGLDDLRHQSSGTVWLKHQHDRVCGDTVFQLQENVKDKLRAIVVTLSYGLRTPPLGRQAPGQELPTVAPILNAHQPSTQRTEIHFLKQGCGQDKICQSNLQLERYQFCSRISDTEFQALPMDLDGRTALFALSGQPFIGLELTVTNLPSDPSRPQADGDDAHEAQLLVTLPASLRYSGVRALDSVEKPLCLSNDSASHVECELGNPMKRGAQVTFYLILSTSGITIETTELEVKLLLATISEQELDPVSVRAHVFIELPLSISGVATPQQLFFSGEVKGESAMRSERELGRKVKYEVTVSNQGQSLNTLGSANLNIMWPHEIANGKWLLYPMRVELEGGQGPGKRGICSPRPNILQLDVDSRDRRRRELGQPEPQEPPEKVEPSTSWWPVSSAEKRNMTLDCPRTAKCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYMAVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPMAVVVEGVPWWVILLGVLAGLLVLALLVLLLWKLGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTIQRSNWGNSQWEGSDAHPILAADWHPELGPDGHPVPATA
Tissue specificity：Isoforms containing segment X2 are found in adult heart, lung and skeletal muscle. Isoforms containing segment X1 are expressed in adult heart, lung and in proliferating skeletal myoblasts but not in adult skeletal muscle. Isoforms containing segment a are exclusively found in skeletal muscle. Isoforms containing segment B are widely expressed. In muscle fibers isoforms containing segment A and B are expressed at myotendinous and neuromuscular junctions; isoforms containing segment C are expressed at neuromuscular junctions and at extrasynaptic sites. {ECO:0000269|PubMed:8626012}.
Induction：
Developmental stage：Isoforms are developmentally regulated during the formation of skeletal muscle. Undifferentiated (replicating) myoblasts express isoforms containing segment B only, whereas differentiated myoblasts express isoforms containing segments A or B.
Protein families：Integrin alpha chain family