S22A3_MOUSE Q9WTW5
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UniProt:Q9WTW5
Recommended name：Solute carrier family 22 member 3
EC number：
Alternative names：(Organic cation transporter 3)
Cleaved into：
GeneID：20519
Gene names (primary )：Slc22a3
Gene names (synonym )：44472
Gene names (ORF )：
Length：551
Mass：61053
Sequence：MPTFDQALRKAGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGSQPDYYWCRGPRATALAERCAWSPEEEWNLTTPELHVPAERRGQGHCHRYLLEATNTSSELSCDPLTAFPNRSAPLVSCSGDWRYVETHSTIVSQFDLVCSNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIIYLISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHLSSNYSEITVTDEEVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIGGNLYIDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEGIPWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGILASVCGGLVMLLPETKGIALPETVEDVEKLGSSQLHQCGRKKKTQVSTSDV
Tissue specificity：Highly expressed in placenta and in kidney cortex, but not in medulla. Low levels found in brain. In the kidney, expressed specifically in the proximal and distal convoluted tubules and within Bowman capsule, but not in the glomerulus. {ECO:0000269|PubMed:10966924, ECO:0000269|PubMed:9933568, ECO:0000305}.
Induction：
Developmental stage：Levels are high during gestation, but decrease greatly towards the end of gestation. {ECO:0000269|PubMed:9933568, ECO:0000305}.
Protein families：Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family