VEGFA_MOUSE Q00731
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UniProt:Q00731
Recommended name：Vascular endothelial growth factor A
EC number：
Alternative names：(VEGF-A) (Vascular permeability factor) (VPF)
Cleaved into：
GeneID：22339
Gene names (primary )：Vegfa
Gene names (synonym )：Vegf
Gene names (ORF )：
Length：214
Mass：25283
Sequence：MNFLLSWVHWTLALLLYLHHAKWSQAAPTTEGEQKSHEVIKFMDVYQRSYCRPIETLVDIFQEYPDEIEYIFKPSCVPLMRCAGCCNDEALECVPTSESNITMQIMRIKPHQSQHIGEMSFLQHSRCECRPKKDRTKPEKKSVRGKGKGQKRKRKKSRFKSWSVHCEPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
Tissue specificity：In developing embryos, expressed mainly in the choroid plexus, paraventricular neuroepithelium, placenta and kidney glomeruli. Also found in bronchial epithelium, adrenal gland and in seminiferous tubules of testis. High expression of VEGF continues in kidney glomeruli and choroid plexus in adults.
Induction：By IL-6 and FSH in vitro. {ECO:0000269|PubMed:16259067}.
Developmental stage：Levels increase during pregnancy (maximum 5.5-fold at 5 days) and a more marked increase occurs during lactation (maximal 9.7-fold at 7 days). Levels decrease progressively during the phase of involution. {ECO:0000269|PubMed:10878616}.
Protein families：PDGF/VEGF growth factor family