GHRL_MOUSE   Q9EQX0


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UniProt:Q9EQX0

Recommended name:Appetite-regulating hormone

EC number:

Alternative names:(Growth hormone secretagogue) (Growth hormone-releasing peptide) (Motilin-related peptide) (Protein M46)

Cleaved into:Ghrelin; Obestatin

GeneID:58991

Gene names  (primary ):Ghrl

Gene names  (synonym ):Mtlrp

Gene names  (ORF ):

Length:117

Mass:13207

Sequence:MLSSGTICSLLLLSMLWMDMAMAGSSFLSPEHQKAQQRKESKKPPAKLQPRALEGWLHPEDRGQAEETEEELEIRFNAPFDVGIKLSGAQYQQHGRALGKFLQDILWEEVKEAPADK

Tissue specificity:Mainly expressed in the gastrointestinal tract with higher levels in the stomach, medium levels in the duodenum, jejunum, ileum and colon. Low expression in the testis and brain. Not detected in the salivary gland, pancreas, liver and lung. {ECO:0000269|PubMed:10930375}.

Induction:

Developmental stage:Levels of n-octanoylated and n-decanoylated ghrelin drop by one third and 3-fold, respectively, between postnatal weeks 3 and 4 due to change of diet during weaning. {ECO:0000269|PubMed:15746259}.

Protein families:Motilin family


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