PO5F2_MOUSE   Q9DAC9


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UniProt:Q9DAC9

Recommended name:POU domain, class 5, transcription factor 2

EC number:

Alternative names:(Sperm 1 POU domain transcription factor) (SPRM-1)

Cleaved into:

GeneID:75507

Gene names  (primary ):Pou5f2

Gene names  (synonym ):Sprm1

Gene names  (ORF ):

Length:329

Mass:36411

Sequence:MAGRRSSNVFPLSGNSGGGLEVDTPTWLSSQAATSRLMVRPSMGPGICPGPEVWGVPLGSSPYEFRGGIAPYRACEARAWSQSSSEDTCPGPYIALRYMPNLALPEDVSAIQKEMEQLAKELRQKRMTLGYSQADVGFAVGAMFGKVLSQTTICRFEAQQLSLANMWKLRPLLKMWLEEVDEKNLLGICRMEMILEQARKRRRASRERRIGSNLEKLFLQCPEPTPQQISYIAGRLRLQKDLVQVWFSNRSQMGSWPTNDTSRREDVGATGSPFPGPPVCFPMAPGLHFDFTHYEGSCLTPLYSSTPFPVRGALLSAPTTTLGLPRLSS

Tissue specificity:In adult brain, expressed in the olfactory bulb, becoming specifically concentrated in the mitral cell layer. Also found in the pyramidal cell layer of the hippocampus, in the granule cell layer of the cerebellum and in the cortex. {ECO:0000269|PubMed:7908264}.

Induction:

Developmental stage:Low expression levels observed at 12 dpc in neural tube and brain. On days 15.5 and 16.5, expression levels increased and became localized specifically to the forebrain, with highest levels found in the laminar region of the forebrain cortex. Also expressed in the mitral region of the olfactory bulb. {ECO:0000269|PubMed:7908264}.

Protein families:POU transcription factor family, Class-5 subfamily


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