EMIL2_MOUSE Q8K482
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UniProt:Q8K482
Recommended name:EMILIN-2
EC number:
Alternative names:(Basilin) (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2)
Cleaved into:
GeneID:246707
Gene names (primary ):Emilin2
Gene names (synonym ):
Gene names (ORF ):
Length:1074
Mass:117310
Sequence:MCQETPPRPRAPSRWTPALLALLALGGAGLCHASSQPGYHARPSARNKNWCAYIVNKNVSCTVQEGSESFIQAQYNCPWNQMPCPSALVYRVNFRPRFVTRYKIVTQLEWRCCPGFRGPDCQEGPKDHMKTPRPPSARPKNNLKKATDTDPSQVSQPKKTLSPTNAVEPGQVADAKQGPPELQQSKVQVLEEKVVRLTRMVLDLQSTVVGLKENLKHTIQDDGRKEPDSWLGPLHPQPTPDSPLAGDAEPSQLPGIPSSKESGMKDIKSELAEVKDTLKTKSDKLEELDGKVKGYEGQLKQLQEAAQGPTVTMTTNELYQAYVDSKIDALREELMEGMDRKLADLKNTCEYKLVGLQQQCDDYGSSYLGVIELIGEKEASLKKDIADLRAQLQDPVAQPSCCNGQKSSDFGPQIKALDQKIERVAEATRMLNGRLDNEFDRLSVPEPDADFDARWTELDARINVTEKNAEEHCFYIEETLRGTINGEVDDLRKLLNEKIHSLEDRLGIVLQAANSSDVELTPMGPALPEQPGAENEQVLMELSRLKDKVQVVEDFCLQSLPHGIDGALPSVEDLTHVSLSLLESLNDTMHRQFQETSHSIQKLQEDVNALHSQLNHSECTGTYLQNGVSDSRTGDSMEASGFTKTGEQERTVGTVPSPGTPAAPCCGQLEERWQKLQNQMLAELDTCKESAHGVQSGVSAIEGRVFQLEQTCRRLDTISGSLQRIKEGLGKHVGSLWNCIRQMNGTLKSHSRDISGLKNSVQQFYSHVFQISTDLQDLVKFQPSATEEPSEATEGPSGKTPLESTRPSEEAPTEPPRLTPLPEDPAGPPQTGQQPVLPQRPLQPPPLPAWPGRTGLPFLPGSSGVIMETGEAGPPGRMGVSGRGLPRGVDGQMGQGPIHSSEGYAGAPGYPKSPPVTTPGVPLPTLVSFSAGLTQKPFPSDGGVVLFNKVLVNDGDVYNPNTGIFTAPYDGRYLITATLTPERDTYVEAVLSVSNASVAQLHTAGYRREFLEYHRPPGAVHTCGGPGAFHLIVHLKAGDGVNVVVTGGRLAHTDFDEMYSTFSGVFLYPFLSHL
Tissue specificity:Highest levels are present in cochlea of P8 pups, followed by modest levels in adult heart and lung, and much lower levels in forebrain, brainstem, cerebellum and hypothalamus. Very low levels detected in muscle, liver, kidney and eye.
Induction:
Developmental stage:Low levels detected in cochlea in neonatal pups at P1. Levels increased 2-fold by P5 and rose further to 16-fold at P13. Expression declined somewhat in adult mice. At 9.5 dpc, as during all stages of development, it is strongly expressed in the neural fold, the limbbuds and the heart. {ECO:0000269|PubMed:12221002}.
Protein families: