EED_MOUSE Q921E6
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UniProt:Q921E6
Recommended name：Polycomb protein EED
EC number：
Alternative names：
Cleaved into：
GeneID：13626
Gene names (primary )：Eed
Gene names (synonym )：
Gene names (ORF )：
Length：441
Mass：50198
Sequence：MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
Tissue specificity：Expressed in brain, heart, kidney, liver, lung, muscle, ovary, spleen and testis. Expressed throughout the brain. {ECO:0000269|PubMed:17259173, ECO:0000269|PubMed:8805699, ECO:0000269|PubMed:9234727}.
Induction：Induced in embryonic stem cells (ES cells) by STAT3 and POU5F1. {ECO:0000269|PubMed:18201968}.
Developmental stage：Maternally expressed. Expressed from 5.5 dpc, and expression remains high throughout development. Expression decreases during differentiation of embryonic stem cells (ES cells). Expression increases in prostate during prostate tumor development. {ECO:0000269|PubMed:12689588, ECO:0000269|PubMed:15684044, ECO:0000269|PubMed:8805699}.
Protein families：WD repeat ESC family