LIPL_MOUSE P11152
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UniProt:P11152
Recommended name：Lipoprotein lipase
EC number：EC 3.1.1.34
Alternative names：(LPL) (Phospholipase A1) (EC 3.1.1.32)
Cleaved into：
GeneID：16956
Gene names (primary )：Lpl
Gene names (synonym )：
Gene names (ORF )：
Length：474
Mass：53109
Sequence：MESKALLLVVLGVWLQSLTAFRGGVAAADAGRDFSDIESKFALRTPEDTAEDTCHLIPGLADSVSNCHFNHSSKTFVVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLYRAQQHYPVSAGYTKLVGNDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGVAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTEDGKQHNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMMKLKWISDSYFSWPDWWSSPSFVIERIRVKAGETQKKVIFCAREKVSHLQKGKDSAVFVKCHDKSLKKSG
Tissue specificity：Detected in white and brown adipose tissue and heart muscle, especially at the lumenal surface of capillaries (PubMed:25066055, PubMed:27811232, PubMed:20620994). Detected on capillary endothelium in the lactating mammary gland (PubMed:27811232). Detected in blood plasma (at protein level) (PubMed:17403372, PubMed:25066055). Expressed in liver, epididymal fat, heart, psoas muscle, lactating mammary gland, adrenal, lung, and ovary. Highest levels in heart and adrenal gland. {ECO:0000269|PubMed:17403372, ECO:0000269|PubMed:20620994, ECO:0000269|PubMed:25066055, ECO:0000269|PubMed:2723548, ECO:0000269|PubMed:27811232}.
Induction：
Developmental stage：Maximum expression in adipose tissue during early development. In heart, low levels 6 days before birth increasing 278-fold as animals reach adulthood. {ECO:0000269|PubMed:2723548}.
Protein families：AB hydrolase superfamily, Lipase family