UBP2_MOUSE O88623
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UniProt:O88623
Recommended name：Ubiquitin carboxyl-terminal hydrolase 2
EC number：EC 3.4.19.12
Alternative names：(41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Cleaved into：
GeneID：53376
Gene names (primary )：Usp2
Gene names (synonym )：Ubp41
Gene names (ORF )：MNCb-0190
Length：613
Mass：68845
Sequence：MSQLSSTLKRYTESSRYTDAPYAKPGYGTYTPSSYGANLAASFLEKEKLGFKPVSPTSFLPRPRTYGPSSILDCDRGRPLLRSDIIGSSKRSESQTRGNERPSGSGLNGGSGFSYGVSSNSLSYLPMNARDQGVTLSQKKSNSQSDLARDFSSLRTSDGYRTSEGFRIDPGNLGRSPMLARTRKELCALQGLYQAASRSEYLTDYLENYGRKGSAPQVLTQAPPPSRVPEVLSPTYRPSGRYTLWEKSKGQASGPSRSSSPGRDTMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLGHTSSAHTALMEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFMGYNQQDAQEFLRFLLDGLHNEVNRVAARPKASPETLDHLPDEEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRGYPEVTLMDCMRLFTKEDILDGDEKPTCCRCRARKRCIKKFSVQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPVTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASPPSRM
Tissue specificity：Isoform 1: Expressed in heart, liver, kidney, pancreas and to a lower extent in skeletal muscle, brain and testis (at protein level) (PubMed:14686789). Expressed in testis, brain, heart and skeletal muscle (PubMed:14686789, PubMed:26756164). Not detected in the small intestine (PubMed:26756164). Isoform 2: Expressed in the small intestine (PubMed:26756164). {ECO:0000269|PubMed:14686789, ECO:0000269|PubMed:26756164}.
Induction：[Isoform 2]: Expressed in a circadian manner in the intestine. {ECO:0000269|PubMed:26756164}.
Developmental stage：No stage-dependent developmental pattern of expression is detected. First detected throughout 7.5 dpc embryos. {ECO:0000269|PubMed:14686789}.
Protein families：Peptidase C19 family, USP2 subfamily