CHADL_MOUSE E9Q7T7
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UniProt:E9Q7T7
Recommended name：Chondroadherin-like protein
EC number：
Alternative names：
Cleaved into：
GeneID：214685
Gene names (primary )：Chadl
Gene names (synonym )：SLRR4B
Gene names (ORF )：
Length：748
Mass：81361
Sequence：MERPQSSIWVFMLLLFMVLLQSPAWHVAAQRCPQTCVCDNSRRHVTCRHQNLTEVPNTIPELTQRLDLQGNILKVLPAAAFQDLPHLTHLDLRNCQVEMVAEGAFRGLGRLLLLNLASNRLSTLPQEALDGLGSLRRLELEGNMLEELRPGTFGALGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPLTYTGEEDGLALPGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQGNPLWCACHARPLLEWLVRARVRSDGACRGPRRLRGEALDTLRPSDLRCPGDAAAGDGDGDEDEDRPAGPRAPPLRSPHGEAAWATPCPPACACVAETRHSTCDGRGLQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFLRIPGTALRALPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHITQVSPGALGPARELEKLHLDRNRLREVPTGALEGLPALKELQLSGNPLRALPDGAFQPVGRSLQQLFLNSSDLEQISPRAFSGLGKGLRSLYLHKNQLQSLPAPLGLSGLELVDLSGNPFHCDCQLLPLHRWLTGLNLRVGATCATPPSVRGQKVKVAAPVFEACPGWTARKAKRTPTSRGSARRTPSLSRH
Tissue specificity：Expressed in cartilage, including articular knee cartilage, where it localizes to the extracellular space in the area immediately surrounding the chondrocytes, not detected in any other tissues (at protein level). {ECO:0000269|PubMed:25451920}.
Induction：
Developmental stage：Not detected before 13.5 dpc. From 13.5 dpc on, prominently expressed only in mesenchymal condensations and in cartilaginous tissues. In the ATDC5 cell line model, up-regulated during chondrocyte differentiation, absent in precondrogenic, non-differentiating stage (at protein level). {ECO:0000269|PubMed:25451920}.
Protein families：Small leucine-rich proteoglycan (SLRP) family, SLRP class IV subfamily