TESP1_MOUSE   Q3U132


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UniProt:Q3U132

Recommended name:Protein TESPA1

EC number:

Alternative names:(Thymocyte-expressed positive selection-associated protein 1)

Cleaved into:

GeneID:67596

Gene names  (primary ):Tespa1

Gene names  (synonym ):

Gene names  (ORF ):

Length:458

Mass:51768

Sequence:MEASVLSPTSWEKRRAWLRQSRNWQTQVLEEEAAAALQDALDPEPSSLDDVFQEGNPINKIEDWLQGCGCRDTEEGLSEESGQSNYSGYSSHGTSFEDDLSLGAEATLLSTNGNLFSRNFLQTPRLCQLLDLGSSLASSSMTGGTNKTSSSISEILDQVQEDAEDILFSLGFGHENHKDTSRIPARFFSNPSQAKGINFQLFLKSQVQRMEMEDPCLMLASRFKQVQTLAVTADAFFCLYSYVSKTPVQKFTPSNMFWNFDPTDVPSIRILAPEPEPYSPRERLRRAISKMCLYTGSRDRLSSSYNNPKKNSLDQIVWEVMDRVKGEKIQQDPEHRQALGEESVPPIQNTNPSTSSLPCVSYPKEETQGDMCHAHALARPGPQYHINSTQVRRQLWVLQDINEKPRSAENESPWERKSKARKNLFQRVPVDKNIKSLNLPTIQQKQNQGQARHELTNL

Tissue specificity:Expressed in lymphoid tissues, with highest expression levels detected in thymus and lower levels in spleen and lymph nodes (at protein level). Detected in CD4(+) and CD8(+) T-cells, B-cells and mast cells. Not detected in monocytes/macrophages. {ECO:0000269|PubMed:22561606, ECO:0000269|PubMed:23650607}.

Induction:

Developmental stage:Present in fetal thymus at 14.5 dpc. Expressed during thymocyte maturation, the expression being highest in CD4(+)CD8(+) thymocytes and decreasing with maturation. {ECO:0000269|PubMed:22561606}.

Protein families:


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