TIMP1_MOUSE P12032
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UniProt:P12032
Recommended name：Metalloproteinase inhibitor 1
EC number：
Alternative names：(Collagenase inhibitor 16C8 fibroblast) (Erythroid-potentiating activity) (EPA) (TPA-S1) (TPA-induced protein) (Tissue inhibitor of metalloproteinases 1) (TIMP-1)
Cleaved into：
GeneID：21857
Gene names (primary )：Timp1
Gene names (synonym )：Timp Timp-1
Gene names (ORF )：
Length：205
Mass：22628
Sequence：MMAPFASLASGILLLLSLIASSKACSCAPPHPQTAFCNSDLVIRAKFMGSPEINETTLYQRYKIKMTKMLKGFKAVGNAADIRYAYTPVMESLCGYAHKSQNRSEEFLITGRLRNGNLHISACSFLVPWRTLSPAQQRAFSKTYSAGCGVCTVFPCLSIPCKLESDTHCLWTDQVLVGSEDYQSRHFACLPRNPGLCTWRSLGAR
Tissue specificity：Found in fetal and adult tissues. Highest levels are found in bone. Also found in lung, ovary and uterus.
Induction：Regulated by tumor promoters and mitogens through protein kinase C. Also induced by viruses.
Developmental stage：Present in unfertilized eggs and at the zygote and cleavage stages. Levels increase at the blastocyst stage and with endoderm differentiation. {ECO:0000269|PubMed:2744464}.
Protein families：Protease inhibitor I35 (TIMP) family